Duffner JL - Search Results

1

A robust small-molecule microarray platform for screening cell lysates.

Bradner JE, McPherson OM, Mazitschek R, Barnes-Seeman D, Shen JP, Dhaliwal J, Stevenson KE, Duffner JL, Park SB, Neuberg DS, Nghiem P, Schreiber SL, Koehler AN. Bradner JE, et al. Among authors: duffner jl. Chem Biol. 2006 May;13(5):493-504. doi: 10.1016/j.chembiol.2006.03.004. Chem Biol. 2006. PMID: 16720270

2

A pipeline for ligand discovery using small-molecule microarrays.

Duffner JL, Clemons PA, Koehler AN. Duffner JL, et al. Curr Opin Chem Biol. 2007 Feb;11(1):74-82. doi: 10.1016/j.cbpa.2006.11.031. Epub 2006 Dec 13. Curr Opin Chem Biol. 2007. PMID: 17169601 Review.

3

Binding affinity and kinetic analysis of targeted small molecule-modified nanoparticles.

Tassa C, Duffner JL, Lewis TA, Weissleder R, Schreiber SL, Koehler AN, Shaw SY. Tassa C, et al. Among authors: duffner jl. Bioconjug Chem. 2010 Jan;21(1):14-9. doi: 10.1021/bc900438a. Bioconjug Chem. 2010. PMID: 20028085 Free PMC article.

4

Ring-opening and ring-closing reactions of a shikimic acid-derived substrate leading to diverse small molecules.

Miao H, Tallarico JA, Hayakawa H, Münger K, Duffner JL, Koehler AN, Schreiber SL, Lewis TA. Miao H, et al. Among authors: duffner jl. J Comb Chem. 2007 Mar-Apr;9(2):245-53. doi: 10.1021/cc060135m. J Comb Chem. 2007. PMID: 17348730

5

A small molecule that binds Hedgehog and blocks its signaling in human cells.

Stanton BZ, Peng LF, Maloof N, Nakai K, Wang X, Duffner JL, Taveras KM, Hyman JM, Lee SW, Koehler AN, Chen JK, Fox JL, Mandinova A, Schreiber SL. Stanton BZ, et al. Among authors: duffner jl. Nat Chem Biol. 2009 Mar;5(3):154-6. doi: 10.1038/nchembio.142. Epub 2009 Jan 18. Nat Chem Biol. 2009. PMID: 19151731 Free PMC article.

6

Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity.

Nieland TJ, Shaw JT, Jaipuri FA, Duffner JL, Koehler AN, Banakos S, Zannis VI, Kirchhausen T, Krieger M. Nieland TJ, et al. Among authors: duffner jl. Biochemistry. 2008 Jan 8;47(1):460-72. doi: 10.1021/bi701277x. Epub 2007 Dec 8. Biochemistry. 2008. PMID: 18067275 Free PMC article.

7

Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI.

Nieland TJ, Shaw JT, Jaipuri FA, Maliga Z, Duffner JL, Koehler AN, Krieger M. Nieland TJ, et al. Among authors: duffner jl. J Lipid Res. 2007 Aug;48(8):1832-45. doi: 10.1194/jlr.M700209-JLR200. Epub 2007 May 28. J Lipid Res. 2007. PMID: 17533223 Free article.

8

Synthesis and biological evaluation of a unique heparin mimetic hexasaccharide for structure-activity relationship studies.

Roy S, El Hadri A, Richard S, Denis F, Holte K, Duffner J, Yu F, Galcheva-Gargova Z, Capila I, Schultes B, Petitou M, Kaundinya GV. Roy S, et al. J Med Chem. 2014 Jun 12;57(11):4511-20. doi: 10.1021/jm4016069. Epub 2014 May 19. J Med Chem. 2014. PMID: 24786387

9

Characterization of heparin-protein interaction by saturation transfer difference (STD) NMR.

Yu F, Roy S, Arevalo E, Schaeck J, Wang J, Holte K, Duffner J, Gunay NS, Capila I, Kaundinya GV. Yu F, et al. Anal Bioanal Chem. 2014 May;406(13):3079-89. doi: 10.1007/s00216-014-7729-4. Epub 2014 Mar 25. Anal Bioanal Chem. 2014. PMID: 24664406

10

Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events.

Sobolev O, Binda E, O'Farrell S, Lorenc A, Pradines J, Huang Y, Duffner J, Schulz R, Cason J, Zambon M, Malim MH, Peakman M, Cope A, Capila I, Kaundinya GV, Hayday AC. Sobolev O, et al. Nat Immunol. 2016 Feb;17(2):204-13. doi: 10.1038/ni.3328. Epub 2016 Jan 4. Nat Immunol. 2016. PMID: 26726811 Free PMC article.

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