Mapara MY - Search Results

1

Reduction of graft-versus-host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and involves inhibition of STAT1.

Leng C, Gries M, Ziegler J, Lokshin A, Mascagni P, Lentzsch S, Mapara MY. Leng C, et al. Among authors: mapara my. Exp Hematol. 2006 Jun;34(6):776-87. doi: 10.1016/j.exphem.2006.02.014. Exp Hematol. 2006. PMID: 16728283 Free article.

2

The histone deacetylase inhibitor, PXD101, potentiates bortezomib-induced anti-multiple myeloma effect by induction of oxidative stress and DNA damage.

Feng R, Oton A, Mapara MY, Anderson G, Belani C, Lentzsch S. Feng R, et al. Among authors: mapara my. Br J Haematol. 2007 Nov;139(3):385-97. doi: 10.1111/j.1365-2141.2007.06772.x. Br J Haematol. 2007. PMID: 17910628 Free article.

3

Sequential activation of inflammatory signaling pathways during graft-versus-host disease (GVHD): early role for STAT1 and STAT3.

Ma HH, Ziegler J, Li C, Sepulveda A, Bedeir A, Grandis J, Lentzsch S, Mapara MY. Ma HH, et al. Among authors: mapara my. Cell Immunol. 2011;268(1):37-46. doi: 10.1016/j.cellimm.2011.01.008. Epub 2011 Feb 4. Cell Immunol. 2011. PMID: 21376308 Free PMC article.

4

Absence of Stat1 in donor CD4⁺ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice.

Ma H, Lu C, Ziegler J, Liu A, Sepulveda A, Okada H, Lentzsch S, Mapara MY. Ma H, et al. Among authors: mapara my. J Clin Invest. 2011 Jul;121(7):2554-69. doi: 10.1172/JCI43706. Epub 2011 Jun 13. J Clin Invest. 2011. PMID: 21670504 Free PMC article.

5

Combined positive/negative purging and transplantation of peripheral blood progenitor cell autografts in breast cancer patients: a pilot study.

Mapara MY, Körner IJ, Lentzsch S, Krahl D, Reichardt P, Dörken B. Mapara MY, et al. Exp Hematol. 1999 Jan;27(1):169-75. doi: 10.1016/s0301-472x(98)00067-8. Exp Hematol. 1999. PMID: 9923456 Free article. Clinical Trial.

6

Macrophage inflammatory protein 1-alpha (MIP-1 alpha ) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells.

Lentzsch S, Gries M, Janz M, Bargou R, Dörken B, Mapara MY. Lentzsch S, et al. Among authors: mapara my. Blood. 2003 May 1;101(9):3568-73. doi: 10.1182/blood-2002-08-2383. Epub 2002 Dec 27. Blood. 2003. PMID: 12506012 Free article.

7

SDX-308, a nonsteroidal anti-inflammatory agent, inhibits NF-kappaB activity, resulting in strong inhibition of osteoclast formation/activity and multiple myeloma cell growth.

Feng R, Anderson G, Xiao G, Elliott G, Leoni L, Mapara MY, Roodman GD, Lentzsch S. Feng R, et al. Among authors: mapara my. Blood. 2007 Mar 1;109(5):2130-8. doi: 10.1182/blood-2006-07-027458. Epub 2006 Nov 9. Blood. 2007. PMID: 17095620 Free article.

8

KD5170, a novel mercaptoketone-based histone deacetylase inhibitor, exerts antimyeloma effects by DNA damage and mitochondrial signaling.

Feng R, Ma H, Hassig CA, Payne JE, Smith ND, Mapara MY, Hager JH, Lentzsch S. Feng R, et al. Among authors: mapara my. Mol Cancer Ther. 2008 Jun;7(6):1494-505. doi: 10.1158/1535-7163.MCT-08-0183. Mol Cancer Ther. 2008. PMID: 18566220

9

Expression of chemokines in GVHD target organs is influenced by conditioning and genetic factors and amplified by GVHR.

Mapara MY, Leng C, Kim YM, Bronson R, Lokshin A, Luster A, Sykes M. Mapara MY, et al. Biol Blood Marrow Transplant. 2006 Jun;12(6):623-34. doi: 10.1016/j.bbmt.2006.02.005. Biol Blood Marrow Transplant. 2006. PMID: 16737935 Free article.

10

Targeting the microtubular network as a new antimyeloma strategy.

Feng R, Li S, Lu C, Andreas C, Stolz DB, Mapara MY, Lentzsch S. Feng R, et al. Among authors: mapara my. Mol Cancer Ther. 2011 Oct;10(10):1886-96. doi: 10.1158/1535-7163.MCT-11-0234. Epub 2011 Aug 8. Mol Cancer Ther. 2011. PMID: 21825007

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