Weinstein H - Search Results

1

State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.

Quick M, Yano H, Goldberg NR, Duan L, Beuming T, Shi L, Weinstein H, Javitch JA. Quick M, et al. Among authors: weinstein h. J Biol Chem. 2006 Sep 8;281(36):26444-54. doi: 10.1074/jbc.M602438200. Epub 2006 Jun 23. J Biol Chem. 2006. PMID: 16798738 Free article.

2

An intracellular interaction network regulates conformational transitions in the dopamine transporter.

Kniazeff J, Shi L, Loland CJ, Javitch JA, Weinstein H, Gether U. Kniazeff J, et al. Among authors: weinstein h. J Biol Chem. 2008 Jun 20;283(25):17691-701. doi: 10.1074/jbc.M800475200. Epub 2008 Apr 21. J Biol Chem. 2008. PMID: 18426798 Free PMC article.

3

The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site.

Shi L, Quick M, Zhao Y, Weinstein H, Javitch JA. Shi L, et al. Among authors: weinstein h. Mol Cell. 2008 Jun 20;30(6):667-77. doi: 10.1016/j.molcel.2008.05.008. Mol Cell. 2008. PMID: 18570870 Free PMC article.

4

Substrate-dependent proton antiport in neurotransmitter:sodium symporters.

Zhao Y, Quick M, Shi L, Mehler EL, Weinstein H, Javitch JA. Zhao Y, et al. Among authors: weinstein h. Nat Chem Biol. 2010 Feb;6(2):109-16. doi: 10.1038/nchembio.284. Epub 2009 Dec 27. Nat Chem Biol. 2010. PMID: 20081826 Free PMC article.

5

Single-molecule dynamics of gating in a neurotransmitter transporter homologue.

Zhao Y, Terry D, Shi L, Weinstein H, Blanchard SC, Javitch JA. Zhao Y, et al. Among authors: weinstein h. Nature. 2010 May 13;465(7295):188-93. doi: 10.1038/nature09057. Nature. 2010. PMID: 20463731 Free PMC article.

6

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue.

Zhao Y, Terry DS, Shi L, Quick M, Weinstein H, Blanchard SC, Javitch JA. Zhao Y, et al. Among authors: weinstein h. Nature. 2011 Jun 2;474(7349):109-13. doi: 10.1038/nature09971. Epub 2011 Apr 24. Nature. 2011. PMID: 21516104 Free PMC article.

7

Experimental conditions can obscure the second high-affinity site in LeuT.

Quick M, Shi L, Zehnpfennig B, Weinstein H, Javitch JA. Quick M, et al. Among authors: weinstein h. Nat Struct Mol Biol. 2012 Jan 15;19(2):207-11. doi: 10.1038/nsmb.2197. Nat Struct Mol Biol. 2012. PMID: 22245968 Free PMC article.

8

Steric hindrance mutagenesis in the conserved extracellular vestibule impedes allosteric binding of antidepressants to the serotonin transporter.

Plenge P, Shi L, Beuming T, Te J, Newman AH, Weinstein H, Gether U, Loland CJ. Plenge P, et al. Among authors: weinstein h. J Biol Chem. 2012 Nov 16;287(47):39316-26. doi: 10.1074/jbc.M112.371765. Epub 2012 Sep 24. J Biol Chem. 2012. PMID: 23007398 Free PMC article.

9

Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation.

Dehnes Y, Shan J, Beuming T, Shi L, Weinstein H, Javitch JA. Dehnes Y, et al. Among authors: weinstein h. Neurochem Int. 2014 Jul;73:4-15. doi: 10.1016/j.neuint.2014.02.003. Epub 2014 Feb 24. Neurochem Int. 2014. PMID: 24576496 Free PMC article.

10

Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters.

Stolzenberg S, Quick M, Zhao C, Gotfryd K, Khelashvili G, Gether U, Loland CJ, Javitch JA, Noskov S, Weinstein H, Shi L. Stolzenberg S, et al. Among authors: weinstein h. J Biol Chem. 2015 May 29;290(22):13992-4003. doi: 10.1074/jbc.M114.625343. Epub 2015 Apr 13. J Biol Chem. 2015. PMID: 25869126 Free PMC article.

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