Howells RD - Search Results

1

Discovery of novel triazole-based opioid receptor antagonists.

Zhang Q, Keenan SM, Peng Y, Nair AC, Yu SJ, Howells RD, Welsh WJ. Zhang Q, et al. Among authors: howells rd. J Med Chem. 2006 Jul 13;49(14):4044-7. doi: 10.1021/jm0601250. J Med Chem. 2006. PMID: 16821764 Free PMC article.

2

Purification and mass spectrometric analysis of the mu opioid receptor.

Christoffers KH, Li H, Keenan SM, Howells RD. Christoffers KH, et al. Among authors: howells rd. Brain Res Mol Brain Res. 2003 Oct 21;118(1-2):119-31. doi: 10.1016/j.molbrainres.2003.08.008. Brain Res Mol Brain Res. 2003. PMID: 14559361

3

Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways.

Peng Y, Zhang Q, Arora S, Keenan SM, Kortagere S, Wannemacher KM, Howells RD, Welsh WJ. Peng Y, et al. Among authors: howells rd. Bioorg Med Chem. 2009 Sep 1;17(17):6442-50. doi: 10.1016/j.bmc.2009.07.007. Epub 2009 Jul 9. Bioorg Med Chem. 2009. PMID: 19646882

4

Identification of an irreversible PPARγ antagonist with potent anticancer activity.

Peng Y, Zhang Q, Zielinski RM, Howells RD, Welsh WJ. Peng Y, et al. Among authors: howells rd. Pharmacol Res Perspect. 2020 Dec;8(6):e00693. doi: 10.1002/prp2.693. Pharmacol Res Perspect. 2020. PMID: 33280279 Free PMC article. Review.

5

Proteasome involvement in agonist-induced down-regulation of mu and delta opioid receptors.

Chaturvedi K, Bandari P, Chinen N, Howells RD. Chaturvedi K, et al. Among authors: howells rd. J Biol Chem. 2001 Apr 13;276(15):12345-55. doi: 10.1074/jbc.M008054200. Epub 2001 Jan 10. J Biol Chem. 2001. PMID: 11152677 Free article.

6

Studies on inhibition of mu and delta opioid receptor binding by dithiothreitol and N-ethylmaleimide. His223 is critical for mu opioid receptor binding and inactivation by N-ethylmaleimide.

Shahrestanifar M, Wang WW, Howells RD. Shahrestanifar M, et al. Among authors: howells rd. J Biol Chem. 1996 Mar 8;271(10):5505-12. doi: 10.1074/jbc.271.10.5505. J Biol Chem. 1996. PMID: 8621408 Free article.

7

Purification and mass spectrometric analysis of the delta opioid receptor.

Christoffers KH, Li H, Howells RD. Christoffers KH, et al. Among authors: howells rd. Brain Res Mol Brain Res. 2005 May 20;136(1-2):54-64. doi: 10.1016/j.molbrainres.2005.01.016. Epub 2005 Mar 2. Brain Res Mol Brain Res. 2005. PMID: 15893587

8

Sensitivity of opioid receptor binding to N-substituted maleimides and methanethiosulfonate derivatives.

Shahrestanifar MS, Howells RD. Shahrestanifar MS, et al. Among authors: howells rd. Neurochem Res. 1996 Nov;21(11):1295-9. doi: 10.1007/BF02532370. Neurochem Res. 1996. PMID: 8947919

9

Inhibition of mu and delta opioid receptor ligand binding by the peptide aldehyde protease inhibitor, leupeptin.

Christoffers KH, Khokhar A, Chaturvedi K, Howells RD. Christoffers KH, et al. Among authors: howells rd. Regul Pept. 2002 Apr 15;105(1):9-14. doi: 10.1016/s0167-0115(01)00382-2. Regul Pept. 2002. PMID: 11853866

10

Inhibition of agonist-induced down-regulation of the delta-opioid receptor with a proteasome inhibitor attenuates opioid tolerance in human embryonic kidney 293 cells.

Yadav PN, Chaturvedi K, Howells RD. Yadav PN, et al. Among authors: howells rd. J Pharmacol Exp Ther. 2007 Mar;320(3):1186-94. doi: 10.1124/jpet.106.113621. Epub 2006 Dec 11. J Pharmacol Exp Ther. 2007. PMID: 17159161

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