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Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography.
Podust LM, von Kries JP, Eddine AN, Kim Y, Yermalitskaya LV, Kuehne R, Ouellet H, Warrier T, Alteköster M, Lee JS, Rademann J, Oschkinat H, Kaufmann SH, Waterman MR. Podust LM, et al. Among authors: kim y. Antimicrob Agents Chemother. 2007 Nov;51(11):3915-23. doi: 10.1128/AAC.00311-07. Epub 2007 Sep 10. Antimicrob Agents Chemother. 2007. PMID: 17846131 Free PMC article.
Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis.
Pfleger BF, Kim Y, Nusca TD, Maltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, Bergman NH, Hanna PC, Joachimiak A, Sherman DH. Pfleger BF, et al. Among authors: kim y. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17133-8. doi: 10.1073/pnas.0808118105. Epub 2008 Oct 27. Proc Natl Acad Sci U S A. 2008. PMID: 18955706 Free PMC article.
Functional and structural analysis of the siderophore synthetase AsbB through reconstitution of the petrobactin biosynthetic pathway from Bacillus anthracis.
Nusca TD, Kim Y, Maltseva N, Lee JY, Eschenfeldt W, Stols L, Schofield MM, Scaglione JB, Dixon SD, Oves-Costales D, Challis GL, Hanna PC, Pfleger BF, Joachimiak A, Sherman DH. Nusca TD, et al. Among authors: kim y. J Biol Chem. 2012 May 4;287(19):16058-72. doi: 10.1074/jbc.M112.359349. Epub 2012 Mar 9. J Biol Chem. 2012. PMID: 22408253 Free PMC article.
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