Sherman DH - Search Results

1

The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae.

Sherman DH, Li S, Yermalitskaya LV, Kim Y, Smith JA, Waterman MR, Podust LM. Sherman DH, et al. J Biol Chem. 2006 Sep 8;281(36):26289-97. doi: 10.1074/jbc.M605478200. Epub 2006 Jul 6. J Biol Chem. 2006. PMID: 16825192 Free PMC article.

2

Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae.

Xue Y, Wilson D, Zhao L, Liu Hw, Sherman DH. Xue Y, et al. Among authors: sherman dh. Chem Biol. 1998 Nov;5(11):661-7. doi: 10.1016/s1074-5521(98)90293-9. Chem Biol. 1998. PMID: 9831532

3

Mechanisms of molecular recognition in the pikromycin polyketide synthase.

Chen S, Xue Y, Sherman DH, Reynolds KA. Chen S, et al. Among authors: sherman dh. Chem Biol. 2000 Dec;7(12):907-18. doi: 10.1016/s1074-5521(00)00039-9. Chem Biol. 2000. PMID: 11137814

4

Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin.

Kim BS, Cropp TA, Beck BJ, Sherman DH, Reynolds KA. Kim BS, et al. Among authors: sherman dh. J Biol Chem. 2002 Dec 13;277(50):48028-34. doi: 10.1074/jbc.M207770200. Epub 2002 Oct 3. J Biol Chem. 2002. PMID: 12368286 Free article.

5

The 1.92-A structure of Streptomyces coelicolor A3(2) CYP154C1. A new monooxygenase that functionalizes macrolide ring systems.

Podust LM, Kim Y, Arase M, Neely BA, Beck BJ, Bach H, Sherman DH, Lamb DC, Kelly SL, Waterman MR. Podust LM, et al. Among authors: sherman dh. J Biol Chem. 2003 Apr 4;278(14):12214-21. doi: 10.1074/jbc.M212210200. Epub 2003 Jan 7. J Biol Chem. 2003. PMID: 12519772 Free article.

6

Comparison of the 1.85 A structure of CYP154A1 from Streptomyces coelicolor A3(2) with the closely related CYP154C1 and CYPs from antibiotic biosynthetic pathways.

Podust LM, Bach H, Kim Y, Lamb DC, Arase M, Sherman DH, Kelly SL, Waterman MR. Podust LM, et al. Among authors: sherman dh. Protein Sci. 2004 Jan;13(1):255-68. doi: 10.1110/ps.03384804. Protein Sci. 2004. PMID: 14691240 Free PMC article.

7

Structural basis for macrolactonization by the pikromycin thioesterase.

Akey DL, Kittendorf JD, Giraldes JW, Fecik RA, Sherman DH, Smith JL. Akey DL, et al. Among authors: sherman dh. Nat Chem Biol. 2006 Oct;2(10):537-42. doi: 10.1038/nchembio824. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969372

8

Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor RppA, a bacterial type III polyketide synthase.

Li S, Grüschow S, Dordick JS, Sherman DH. Li S, et al. Among authors: sherman dh. J Biol Chem. 2007 Apr 27;282(17):12765-72. doi: 10.1074/jbc.M700393200. Epub 2007 Mar 1. J Biol Chem. 2007. PMID: 17331946 Free article.

9

Analysis of a parallel branch in the mitomycin biosynthetic pathway involving the mitN-encoded aziridine N-methyltransferase.

Sitachitta N, Lopanik NB, Mao Y, Sherman DH. Sitachitta N, et al. Among authors: sherman dh. J Biol Chem. 2007 Jul 20;282(29):20941-7. doi: 10.1074/jbc.M702456200. Epub 2007 May 16. J Biol Chem. 2007. PMID: 17507379 Free article.

10

Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase.

Kittendorf JD, Beck BJ, Buchholz TJ, Seufert W, Sherman DH. Kittendorf JD, et al. Among authors: sherman dh. Chem Biol. 2007 Aug;14(8):944-54. doi: 10.1016/j.chembiol.2007.07.013. Chem Biol. 2007. PMID: 17719493 Free PMC article.

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