Herlyn M - Search Results

1

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.

Hoek KS, Schlegel NC, Brafford P, Sucker A, Ugurel S, Kumar R, Weber BL, Nathanson KL, Phillips DJ, Herlyn M, Schadendorf D, Dummer R. Hoek KS, et al. Among authors: herlyn m. Pigment Cell Res. 2006 Aug;19(4):290-302. doi: 10.1111/j.1600-0749.2006.00322.x. Pigment Cell Res. 2006. PMID: 16827748

2

BRAF and RAS mutations in human lung cancer and melanoma.

Brose MS, Volpe P, Feldman M, Kumar M, Rishi I, Gerrero R, Einhorn E, Herlyn M, Minna J, Nicholson A, Roth JA, Albelda SM, Davies H, Cox C, Brignell G, Stephens P, Futreal PA, Wooster R, Stratton MR, Weber BL. Brose MS, et al. Among authors: herlyn m. Cancer Res. 2002 Dec 1;62(23):6997-7000. Cancer Res. 2002. PMID: 12460918

3

Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation.

Satyamoorthy K, Li G, Gerrero MR, Brose MS, Volpe P, Weber BL, Van Belle P, Elder DE, Herlyn M. Satyamoorthy K, et al. Among authors: herlyn m. Cancer Res. 2003 Feb 15;63(4):756-9. Cancer Res. 2003. PMID: 12591721

4

BRAF as a potential therapeutic target in melanoma and other malignancies.

Tuveson DA, Weber BL, Herlyn M. Tuveson DA, et al. Among authors: herlyn m. Cancer Cell. 2003 Aug;4(2):95-8. doi: 10.1016/s1535-6108(03)00189-2. Cancer Cell. 2003. PMID: 12957284 Free article. Review. No abstract available.

5

Absence of BRAF mutations in UV-protected mucosal melanomas.

Edwards RH, Ward MR, Wu H, Medina CA, Brose MS, Volpe P, Nussen-Lee S, Haupt HM, Martin AM, Herlyn M, Lessin SR, Weber BL. Edwards RH, et al. Among authors: herlyn m. J Med Genet. 2004 Apr;41(4):270-2. doi: 10.1136/jmg.2003.016667. J Med Genet. 2004. PMID: 15060100 Free PMC article.

6

Gene expression profiling of melanoma cells - searching the haystack.

Brafford P, Herlyn M. Brafford P, et al. Among authors: herlyn m. J Transl Med. 2005 Jan 13;3(1):2. doi: 10.1186/1479-5876-3-2. J Transl Med. 2005. PMID: 15649323 Free PMC article.

7

Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion.

Smalley KS, Brafford P, Haass NK, Brandner JM, Brown E, Herlyn M. Smalley KS, et al. Among authors: herlyn m. Am J Pathol. 2005 May;166(5):1541-54. doi: 10.1016/S0002-9440(10)62370-X. Am J Pathol. 2005. PMID: 15855653 Free PMC article.

8

Selective evolutionary pressure from the tissue microenvironment drives tumor progression.

Smalley KS, Brafford PA, Herlyn M. Smalley KS, et al. Among authors: herlyn m. Semin Cancer Biol. 2005 Dec;15(6):451-9. doi: 10.1016/j.semcancer.2005.06.002. Semin Cancer Biol. 2005. PMID: 16043361 Review.

9

Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression.

Liu ZJ, Xiao M, Balint K, Smalley KS, Brafford P, Qiu R, Pinnix CC, Li X, Herlyn M. Liu ZJ, et al. Among authors: herlyn m. Cancer Res. 2006 Apr 15;66(8):4182-90. doi: 10.1158/0008-5472.CAN-05-3589. Cancer Res. 2006. PMID: 16618740

10

Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases.

Smalley KS, Haass NK, Brafford PA, Lioni M, Flaherty KT, Herlyn M. Smalley KS, et al. Among authors: herlyn m. Mol Cancer Ther. 2006 May;5(5):1136-44. doi: 10.1158/1535-7163.MCT-06-0084. Mol Cancer Ther. 2006. PMID: 16731745

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