Ungell AL - Search Results

1

The potential inhibitory effect of antiparasitic drugs and natural products on P-glycoprotein mediated efflux.

Hayeshi R, Masimirembwa C, Mukanganyama S, Ungell AL. Hayeshi R, et al. Among authors: ungell al. Eur J Pharm Sci. 2006 Sep;29(1):70-81. doi: 10.1016/j.ejps.2006.05.009. Epub 2006 Jun 3. Eur J Pharm Sci. 2006. PMID: 16846720

2

Lysosomal trapping of amodiaquine: impact on transport across intestinal epithelia models.

Hayeshi R, Masimirembwa C, Mukanganyama S, Ungell AL. Hayeshi R, et al. Among authors: ungell al. Biopharm Drug Dispos. 2008 Sep;29(6):324-34. doi: 10.1002/bdd.616. Biopharm Drug Dispos. 2008. PMID: 18570280

3

In vitro and in silico identification and characterization of thiabendazole as a mechanism-based inhibitor of CYP1A2 and simulation of possible pharmacokinetic drug-drug interactions.

Thelingwani RS, Zvada SP, Dolgos H, Ungell AL, Masimirembwa CM. Thelingwani RS, et al. Among authors: ungell al. Drug Metab Dispos. 2009 Jun;37(6):1286-94. doi: 10.1124/dmd.108.024604. Epub 2009 Mar 19. Drug Metab Dispos. 2009. PMID: 19299526

4

Induction of metabolism and transport in human intestine: validation of precision-cut slices as a tool to study induction of drug metabolism in human intestine in vitro.

van de Kerkhof EG, de Graaf IA, Ungell AL, Groothuis GM. van de Kerkhof EG, et al. Among authors: ungell al. Drug Metab Dispos. 2008 Mar;36(3):604-13. doi: 10.1124/dmd.107.018820. Epub 2007 Dec 19. Drug Metab Dispos. 2008. PMID: 18094037

5

Innovative methods to study human intestinal drug metabolism in vitro: precision-cut slices compared with ussing chamber preparations.

van de Kerkhof EG, Ungell AL, Sjöberg AK, de Jager MH, Hilgendorf C, de Graaf IA, Groothuis GM. van de Kerkhof EG, et al. Among authors: ungell al. Drug Metab Dispos. 2006 Nov;34(11):1893-902. doi: 10.1124/dmd.106.011148. Epub 2006 Aug 16. Drug Metab Dispos. 2006. PMID: 16914511

6

Single‑Dose Pharmacokinetics and Safety of the Oral Galectin‑3 Inhibitor, Selvigaltin (GB1211), in Participants with Hepatic Impairment.

Aslanis V, Gray M, Slack RJ, Zetterberg FR, Tonev D, Phung D, Smith B, Jacoby B, Schambye H, Krastev Z, Ungell AL, Lindmark B. Aslanis V, et al. Among authors: ungell al. Clin Drug Investig. 2024 Oct;44(10):773-787. doi: 10.1007/s40261-024-01395-7. Epub 2024 Oct 2. Clin Drug Investig. 2024. PMID: 39358661 Clinical Trial.

7

A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age-dependent differences in absorption.

Streekstra EJ, Kiss M, van den Heuvel J, Nicolaï J, van den Broek P, Botden SMBI, Stommel MWJ, van Rijssel L, Ungell AL, van de Steeg E, Russel FGM, de Wildt SN. Streekstra EJ, et al. Among authors: ungell al. Clin Transl Sci. 2022 Oct;15(10):2392-2402. doi: 10.1111/cts.13368. Epub 2022 Aug 12. Clin Transl Sci. 2022. PMID: 35962572 Free PMC article.

8

Review of paediatric gastrointestinal physiology relevant to the absorption of orally administered medicines.

Wollmer E, Ungell AL, Nicolas JM, Klein S. Wollmer E, et al. Among authors: ungell al. Adv Drug Deliv Rev. 2022 Feb;181:114084. doi: 10.1016/j.addr.2021.114084. Epub 2021 Dec 17. Adv Drug Deliv Rev. 2022. PMID: 34929252 Review.

9

Ontogeny of Small Intestinal Drug Transporters and Metabolizing Enzymes Based on Targeted Quantitative Proteomics.

Kiss M, Mbasu R, Nicolaï J, Barnouin K, Kotian A, Mooij MG, Kist N, Wijnen RMH, Ungell AL, Cutler P, Russel FGM, de Wildt SN. Kiss M, et al. Among authors: ungell al. Drug Metab Dispos. 2021 Dec;49(12):1038-1046. doi: 10.1124/dmd.121.000559. Epub 2021 Sep 21. Drug Metab Dispos. 2021. PMID: 34548392

10

Impact of In Vitro Passive Permeability in a P-gp-transfected LLC-PK1 Model on the Prediction of the Rat and Human Unbound Brain-to-Plasma Concentration Ratio.

Nicolaï J, Chapy H, Gillent E, Saunders K, Ungell AL, Nicolas JM, Chanteux H. Nicolaï J, et al. Among authors: ungell al. Pharm Res. 2020 Aug 27;37(9):175. doi: 10.1007/s11095-020-02867-z. Pharm Res. 2020. PMID: 32856111

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