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Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis.
Heymans S, Pauschinger M, De Palma A, Kallwellis-Opara A, Rutschow S, Swinnen M, Vanhoutte D, Gao F, Torpai R, Baker AH, Padalko E, Neyts J, Schultheiss HP, Van de Werf F, Carmeliet P, Pinto YM. Heymans S, et al. Among authors: gao f. Circulation. 2006 Aug 8;114(6):565-73. doi: 10.1161/CIRCULATIONAHA.105.591032. Epub 2006 Jul 31. Circulation. 2006. PMID: 16880329
Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart.
Heymans S, Schroen B, Vermeersch P, Milting H, Gao F, Kassner A, Gillijns H, Herijgers P, Flameng W, Carmeliet P, Van de Werf F, Pinto YM, Janssens S. Heymans S, et al. Among authors: gao f. Circulation. 2005 Aug 23;112(8):1136-44. doi: 10.1161/CIRCULATIONAHA.104.516963. Epub 2005 Aug 15. Circulation. 2005. PMID: 16103240
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