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Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway.
Schnidar H, Eberl M, Klingler S, Mangelberger D, Kasper M, Hauser-Kronberger C, Regl G, Kroismayr R, Moriggl R, Sibilia M, Aberger F. Schnidar H, et al. Among authors: klingler s. Cancer Res. 2009 Feb 15;69(4):1284-92. doi: 10.1158/0008-5472.CAN-08-2331. Epub 2009 Feb 3. Cancer Res. 2009. PMID: 19190345 Free PMC article.
Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells.
Eberl M, Klingler S, Mangelberger D, Loipetzberger A, Damhofer H, Zoidl K, Schnidar H, Hache H, Bauer HC, Solca F, Hauser-Kronberger C, Ermilov AN, Verhaegen ME, Bichakjian CK, Dlugosz AA, Nietfeld W, Sibilia M, Lehrach H, Wierling C, Aberger F. Eberl M, et al. Among authors: klingler s. EMBO Mol Med. 2012 Mar;4(3):218-33. doi: 10.1002/emmm.201100201. Epub 2012 Feb 1. EMBO Mol Med. 2012. PMID: 22294553 Free PMC article.
Organoids for Modeling (Colorectal) Cancer in a Dish.
Rathje F, Klingler S, Aberger F. Rathje F, et al. Among authors: klingler s. Cancers (Basel). 2022 Nov 3;14(21):5416. doi: 10.3390/cancers14215416. Cancers (Basel). 2022. PMID: 36358834 Free PMC article. Review.
Tumor stroma-derived Wnt5a induces differentiation of basal cell carcinoma of Ptch-mutant mice via CaMKII.
Nitzki F, Zibat A, König S, Wijgerde M, Rosenberger A, Brembeck FH, Carstens PO, Frommhold A, Uhmann A, Klingler S, Reifenberger J, Pukrop T, Aberger F, Schulz-Schaeffer W, Hahn H. Nitzki F, et al. Among authors: klingler s. Cancer Res. 2010 Apr 1;70(7):2739-48. doi: 10.1158/0008-5472.CAN-09-3743. Epub 2010 Mar 16. Cancer Res. 2010. PMID: 20233865
Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma.
Singh DK, Kollipara RK, Vemireddy V, Yang XL, Sun Y, Regmi N, Klingler S, Hatanpaa KJ, Raisanen J, Cho SK, Sirasanagandla S, Nannepaga S, Piccirillo S, Mashimo T, Wang S, Humphries CG, Mickey B, Maher EA, Zheng H, Kim RS, Kittler R, Bachoo RM. Singh DK, et al. Among authors: klingler s. Cell Rep. 2017 Jan 24;18(4):961-976. doi: 10.1016/j.celrep.2016.12.064. Cell Rep. 2017. PMID: 28122245 Free PMC article.
Organoids Reveal That Inherent Radiosensitivity of Small and Large Intestinal Stem Cells Determines Organ Sensitivity.
Martin ML, Adileh M, Hsu KS, Hua G, Lee SG, Li C, Fuller JD, Rotolo JA, Bodo S, Klingler S, Haimovitz-Friedman A, Deasy JO, Fuks Z, Paty PB, Kolesnick RN. Martin ML, et al. Among authors: klingler s. Cancer Res. 2020 Mar 1;80(5):1219-1227. doi: 10.1158/0008-5472.CAN-19-0312. Epub 2019 Nov 5. Cancer Res. 2020. PMID: 31690670 Free PMC article.
46 results