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Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.
Overwijk WW, Theoret MR, Finkelstein SE, Surman DR, de Jong LA, Vyth-Dreese FA, Dellemijn TA, Antony PA, Spiess PJ, Palmer DC, Heimann DM, Klebanoff CA, Yu Z, Hwang LN, Feigenbaum L, Kruisbeek AM, Rosenberg SA, Restifo NP. Overwijk WW, et al. Among authors: rosenberg sa. J Exp Med. 2003 Aug 18;198(4):569-80. doi: 10.1084/jem.20030590. J Exp Med. 2003. PMID: 12925674 Free PMC article.
IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells.
Klebanoff CA, Finkelstein SE, Surman DR, Lichtman MK, Gattinoni L, Theoret MR, Grewal N, Spiess PJ, Antony PA, Palmer DC, Tagaya Y, Rosenberg SA, Waldmann TA, Restifo NP. Klebanoff CA, et al. Among authors: rosenberg sa. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1969-74. doi: 10.1073/pnas.0307298101. Epub 2004 Feb 4. Proc Natl Acad Sci U S A. 2004. PMID: 14762166 Free PMC article.
CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.
Antony PA, Piccirillo CA, Akpinarli A, Finkelstein SE, Speiss PJ, Surman DR, Palmer DC, Chan CC, Klebanoff CA, Overwijk WW, Rosenberg SA, Restifo NP. Antony PA, et al. Among authors: rosenberg sa. J Immunol. 2005 Mar 1;174(5):2591-601. doi: 10.4049/jimmunol.174.5.2591. J Immunol. 2005. PMID: 15728465 Free PMC article.
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells.
Klebanoff CA, Gattinoni L, Torabi-Parizi P, Kerstann K, Cardones AR, Finkelstein SE, Palmer DC, Antony PA, Hwang ST, Rosenberg SA, Waldmann TA, Restifo NP. Klebanoff CA, et al. Among authors: rosenberg sa. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9571-6. doi: 10.1073/pnas.0503726102. Epub 2005 Jun 24. Proc Natl Acad Sci U S A. 2005. PMID: 15980149 Free PMC article.
1,359 results