Fersht AR - Search Results

1

Effects of oncogenic mutations and DNA response elements on the binding of p53 to p53-binding protein 2 (53BP2).

Tidow H, Veprintsev DB, Freund SM, Fersht AR. Tidow H, et al. Among authors: fersht ar. J Biol Chem. 2006 Oct 27;281(43):32526-33. doi: 10.1074/jbc.M604725200. Epub 2006 Aug 2. J Biol Chem. 2006. PMID: 16887812 Free article.

2

Crystal structures of engrailed homeodomain mutants: implications for stability and dynamics.

Stollar EJ, Mayor U, Lovell SC, Federici L, Freund SM, Fersht AR, Luisi BF. Stollar EJ, et al. Among authors: fersht ar. J Biol Chem. 2003 Oct 31;278(44):43699-708. doi: 10.1074/jbc.M308029200. Epub 2003 Aug 15. J Biol Chem. 2003. PMID: 12923178 Free article.

3

Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for "mutant conformation".

Friedler A, DeDecker BS, Freund SM, Blair C, Rüdiger S, Fersht AR. Friedler A, et al. Among authors: fersht ar. J Mol Biol. 2004 Feb 6;336(1):187-96. doi: 10.1016/j.jmb.2003.12.005. J Mol Biol. 2004. PMID: 14741214

4

Binding of p53-derived ligands to MDM2 induces a variety of long range conformational changes.

Schon O, Friedler A, Freund S, Fersht AR. Schon O, et al. Among authors: fersht ar. J Mol Biol. 2004 Feb 6;336(1):197-202. doi: 10.1016/j.jmb.2003.11.051. J Mol Biol. 2004. PMID: 14741215

5

Cooperative binding of tetrameric p53 to DNA.

Weinberg RL, Veprintsev DB, Fersht AR. Weinberg RL, et al. Among authors: fersht ar. J Mol Biol. 2004 Aug 27;341(5):1145-59. doi: 10.1016/j.jmb.2004.06.071. J Mol Biol. 2004. PMID: 15321712

6

Regulation of DNA binding of p53 by its C-terminal domain.

Weinberg RL, Freund SM, Veprintsev DB, Bycroft M, Fersht AR. Weinberg RL, et al. Among authors: fersht ar. J Mol Biol. 2004 Sep 17;342(3):801-11. doi: 10.1016/j.jmb.2004.07.042. J Mol Biol. 2004. PMID: 15342238

7

Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53.

Friedler A, Veprintsev DB, Rutherford T, von Glos KI, Fersht AR. Friedler A, et al. Among authors: fersht ar. J Biol Chem. 2005 Mar 4;280(9):8051-9. doi: 10.1074/jbc.M411176200. Epub 2004 Dec 20. J Biol Chem. 2005. PMID: 15611070 Free article.

8

Binding of natively unfolded HIF-1alpha ODD domain to p53.

Sánchez-Puig N, Veprintsev DB, Fersht AR. Sánchez-Puig N, et al. Among authors: fersht ar. Mol Cell. 2005 Jan 7;17(1):11-21. doi: 10.1016/j.molcel.2004.11.019. Mol Cell. 2005. PMID: 15629713 Free article.

9

Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations.

Joerger AC, Ang HC, Veprintsev DB, Blair CM, Fersht AR. Joerger AC, et al. Among authors: fersht ar. J Biol Chem. 2005 Apr 22;280(16):16030-7. doi: 10.1074/jbc.M500179200. Epub 2005 Feb 9. J Biol Chem. 2005. PMID: 15703170 Free article.

10

Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor.

Fernandez-Fernandez MR, Veprintsev DB, Fersht AR. Fernandez-Fernandez MR, et al. Among authors: fersht ar. Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4735-40. doi: 10.1073/pnas.0501459102. Epub 2005 Mar 21. Proc Natl Acad Sci U S A. 2005. PMID: 15781852 Free PMC article.

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