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Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1.
Kayatekin C, Matlack KE, Hesse WR, Guan Y, Chakrabortee S, Russ J, Wanker EE, Shah JV, Lindquist S. Kayatekin C, et al. Among authors: lindquist s. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12085-90. doi: 10.1073/pnas.1412504111. Epub 2014 Aug 4. Proc Natl Acad Sci U S A. 2014. PMID: 25092318 Free PMC article.
Flanking sequences profoundly alter polyglutamine toxicity in yeast.
Duennwald ML, Jagadish S, Muchowski PJ, Lindquist S. Duennwald ML, et al. Among authors: lindquist s. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11045-50. doi: 10.1073/pnas.0604547103. Epub 2006 Jul 10. Proc Natl Acad Sci U S A. 2006. PMID: 16832050 Free PMC article.
A network of protein interactions determines polyglutamine toxicity.
Duennwald ML, Jagadish S, Giorgini F, Muchowski PJ, Lindquist S. Duennwald ML, et al. Among authors: lindquist s. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11051-6. doi: 10.1073/pnas.0604548103. Epub 2006 Jul 10. Proc Natl Acad Sci U S A. 2006. PMID: 16832049 Free PMC article.
Chaperone-dependent amyloid assembly protects cells from prion toxicity.
Douglas PM, Treusch S, Ren HY, Halfmann R, Duennwald ML, Lindquist S, Cyr DM. Douglas PM, et al. Among authors: lindquist s. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7206-11. doi: 10.1073/pnas.0802593105. Epub 2008 May 14. Proc Natl Acad Sci U S A. 2008. PMID: 18480252 Free PMC article.
472 results