Thompson LM - Search Results

1

Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models.

Ehrnhoefer DE, Duennwald M, Markovic P, Wacker JL, Engemann S, Roark M, Legleiter J, Marsh JL, Thompson LM, Lindquist S, Muchowski PJ, Wanker EE. Ehrnhoefer DE, et al. Among authors: thompson lm. Hum Mol Genet. 2006 Sep 15;15(18):2743-51. doi: 10.1093/hmg/ddl210. Epub 2006 Aug 7. Hum Mol Genet. 2006. PMID: 16893904

2

Modeling protein homopolymeric repeats: possible polyglutamine structural motifs for Huntington's disease.

Lathrop RH, Casale M, Tobias DJ, Marsh JL, Thompson LM. Lathrop RH, et al. Among authors: thompson lm. Proc Int Conf Intell Syst Mol Biol. 1998;6:105-14. Proc Int Conf Intell Syst Mol Biol. 1998. PMID: 9783215

3

Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila.

Marsh JL, Walker H, Theisen H, Zhu YZ, Fielder T, Purcell J, Thompson LM. Marsh JL, et al. Among authors: thompson lm. Hum Mol Genet. 2000 Jan 1;9(1):13-25. doi: 10.1093/hmg/9.1.13. Hum Mol Genet. 2000. PMID: 10587574

4

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.

Steffan JS, Kazantsev A, Spasic-Boskovic O, Greenwald M, Zhu YZ, Gohler H, Wanker EE, Bates GP, Housman DE, Thompson LM. Steffan JS, et al. Among authors: thompson lm. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6763-8. doi: 10.1073/pnas.100110097. Proc Natl Acad Sci U S A. 2000. PMID: 10823891 Free PMC article.

5

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.

Steffan JS, Bodai L, Pallos J, Poelman M, McCampbell A, Apostol BL, Kazantsev A, Schmidt E, Zhu YZ, Greenwald M, Kurokawa R, Housman DE, Jackson GR, Marsh JL, Thompson LM. Steffan JS, et al. Among authors: thompson lm. Nature. 2001 Oct 18;413(6857):739-43. doi: 10.1038/35099568. Nature. 2001. PMID: 11607033

6

A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila.

Kazantsev A, Walker HA, Slepko N, Bear JE, Preisinger E, Steffan JS, Zhu YZ, Gertler FB, Housman DE, Marsh JL, Thompson LM. Kazantsev A, et al. Among authors: thompson lm. Nat Genet. 2002 Apr;30(4):367-76. doi: 10.1038/ng864. Epub 2002 Mar 25. Nat Genet. 2002. PMID: 11925563

7

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease.

Hockly E, Richon VM, Woodman B, Smith DL, Zhou X, Rosa E, Sathasivam K, Ghazi-Noori S, Mahal A, Lowden PA, Steffan JS, Marsh JL, Thompson LM, Lewis CM, Marks PA, Bates GP. Hockly E, et al. Among authors: thompson lm. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):2041-6. doi: 10.1073/pnas.0437870100. Epub 2003 Feb 7. Proc Natl Acad Sci U S A. 2003. PMID: 12576549 Free PMC article.

8

Invertebrate models of neurologic disease: insights into pathogenesis and therapy.

Thompson LM, Marsh JL. Thompson LM, et al. Curr Neurol Neurosci Rep. 2003 Sep;3(5):442-8. doi: 10.1007/s11910-003-0028-7. Curr Neurol Neurosci Rep. 2003. PMID: 12914688 Review.

9

Fly models of Huntington's disease.

Marsh JL, Pallos J, Thompson LM. Marsh JL, et al. Among authors: thompson lm. Hum Mol Genet. 2003 Oct 15;12 Spec No 2:R187-93. doi: 10.1093/hmg/ddg271. Epub 2003 Aug 12. Hum Mol Genet. 2003. PMID: 12925571 Review.

10

Altered protein acetylation in polyglutamine diseases.

Bodai L, Pallos J, Thompson LM, Marsh JL. Bodai L, et al. Among authors: thompson lm. Curr Med Chem. 2003 Dec;10(23):2577-87. doi: 10.2174/0929867033456530. Curr Med Chem. 2003. PMID: 14529472 Review.

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