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A hemoglobin-based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus hetastarch (HEX) in a moderate severity hemorrhagic shock swine model with delayed evacuation.
Philbin N, Rice J, Gurney J, McGwin G, Arnaud F, Dong F, Johnson T, Flournoy WS, Ahlers S, Pearce LB, McCarron R, Freilich D. Philbin N, et al. Among authors: pearce lb. Resuscitation. 2005 Sep;66(3):367-78. doi: 10.1016/j.resuscitation.2005.03.019. Resuscitation. 2005. PMID: 16081200
Immune effects of resuscitation with HBOC-201, a hemoglobin-based oxygen carrier, in swine with moderately severe hemorrhagic shock from controlled hemorrhage.
Dong F, Hall CH, Golech SA, Philbin NB, Rice JP, Gurney J, Arnaud FG, Hammett M, Ma X, Flournoy WS, Hong J, Kaplan LJ, Pearce LB, McGwin G, Ahlers S, McCarron R, Freilich D. Dong F, et al. Among authors: pearce lb. Shock. 2006 Jan;25(1):50-5. doi: 10.1097/01.shk.0000187982.56030.94. Shock. 2006. PMID: 16369186
Innate immune responses in Swine resuscitated from severe traumatic hemorrhagic shock with hemoglobin-based oxygen carrier-201.
Hall C, Malkevich N, Handrigan M, Vandermolen C, Aranaud F, Hong J, Dong F, Rice J, Philbin N, Ahlers S, McCarron R, Freilich D, McGwin G, Flournoy WS, Pearce LB. Hall C, et al. Among authors: pearce lb. Artif Cells Blood Substit Immobil Biotechnol. 2007;35(3):259-74. doi: 10.1080/10731190701378568. Artif Cells Blood Substit Immobil Biotechnol. 2007. PMID: 17573626
Immune effects of decreasing low-molecular weight hemoglobin components of hemoglobin-based oxygen carriers (HBOC) in a swine model of severe controlled hemorrhagic shock.
VanderMolen C, Malkevich N, Philbin N, Rice J, Collier S, Hall C, Ahlers S, McCarron R, Freilich D, McGwin G, Pearce LB. VanderMolen C, et al. Among authors: pearce lb. Artif Cells Blood Substit Immobil Biotechnol. 2007;35(5):507-17. doi: 10.1080/10731190701586228. Artif Cells Blood Substit Immobil Biotechnol. 2007. PMID: 17922315
Innate immune response after resuscitation with hemoglobin-based oxygen carrier and recombinant factor VIIA in uncontrolled hemorrhagic shock in a swine model.
Malkevich NV, Dong F, Vandermolen CA, Philbin NB, Rice JP, Scultetus A, Hong J, Arnaud F, Hall CH, McGwin G Jr, Pearce LB, Handrigan M, Ahlers S, McCarron RM, Freilich D. Malkevich NV, et al. Among authors: pearce lb. J Trauma. 2008 Jun;64(6):1498-510. doi: 10.1097/TA.0b013e3181454a05. J Trauma. 2008. PMID: 18545114
Bovine polymerized hemoglobin (hemoglobin-based oxygen carrier-201) resuscitation in three swine models of hemorrhagic shock with militarily relevant delayed evacuation--effects on histopathology and organ function.
Johnson T, Arnaud F, Dong F, Philbin N, Rice J, Asher L, Arrisueno M, Warndorf M, Gurney J, McGwin G, Kaplan L, Flournoy WS, Apple FS, Pearce LB, Ahlers S, McCarron R, Freilich D. Johnson T, et al. Among authors: pearce lb. Crit Care Med. 2006 May;34(5):1464-74. doi: 10.1097/01.CCM.0000215824.85190.89. Crit Care Med. 2006. PMID: 16540964
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