Trudel S - Search Results

1

CHIR-258 is efficacious in a newly developed fibroblast growth factor receptor 3-expressing orthotopic multiple myeloma model in mice.

Xin X, Abrams TJ, Hollenbach PW, Rendahl KG, Tang Y, Oei YA, Embry MG, Swinarski DE, Garrett EN, Pryer NK, Trudel S, Jallal B, Mendel DB, Heise CC. Xin X, et al. Among authors: trudel s. Clin Cancer Res. 2006 Aug 15;12(16):4908-15. doi: 10.1158/1078-0432.CCR-06-0957. Clin Cancer Res. 2006. PMID: 16914579

2

Inhibition of fibroblast growth factor receptor 3 induces differentiation and apoptosis in t(4;14) myeloma.

Trudel S, Ely S, Farooqi Y, Affer M, Robbiani DF, Chesi M, Bergsagel PL. Trudel S, et al. Blood. 2004 May 1;103(9):3521-8. doi: 10.1182/blood-2003-10-3650. Epub 2004 Jan 8. Blood. 2004. PMID: 14715624 Free article.

3

CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma.

Trudel S, Li ZH, Wei E, Wiesmann M, Chang H, Chen C, Reece D, Heise C, Stewart AK. Trudel S, et al. Blood. 2005 Apr 1;105(7):2941-8. doi: 10.1182/blood-2004-10-3913. Epub 2004 Dec 14. Blood. 2005. PMID: 15598814 Free article.

4

MIP-1alpha (CCL3) is a downstream target of FGFR3 and RAS-MAPK signaling in multiple myeloma.

Masih-Khan E, Trudel S, Heise C, Li Z, Paterson J, Nadeem V, Wei E, Roodman D, Claudio JO, Bergsagel PL, Stewart AK. Masih-Khan E, et al. Among authors: trudel s. Blood. 2006 Nov 15;108(10):3465-71. doi: 10.1182/blood-2006-04-017087. Epub 2006 Jul 18. Blood. 2006. PMID: 16849642 Free article.

5

Molecular target characterization and antimyeloma activity of the novel, insulin-like growth factor 1 receptor inhibitor, GTx-134.

Liang SB, Yang XZ, Trieu Y, Li Z, Zive J, Leung-Hagesteijn C, Wei E, Zozulya S, Coss CC, Dalton JT, Fantus IG, Trudel S. Liang SB, et al. Among authors: trudel s. Clin Cancer Res. 2011 Jul 15;17(14):4693-704. doi: 10.1158/1078-0432.CCR-10-3097. Epub 2011 Jun 1. Clin Cancer Res. 2011. PMID: 21632854

6

Overexpression of the myeloma-associated oncogene fibroblast growth factor receptor 3 confers dexamethasone resistance.

Pollett JB, Trudel S, Stern D, Li ZH, Stewart AK. Pollett JB, et al. Among authors: trudel s. Blood. 2002 Nov 15;100(10):3819-21. doi: 10.1182/blood-2002-02-0608. Epub 2002 Jul 25. Blood. 2002. PMID: 12393593 Free article.

7

Preclinical studies of fibroblast growth factor receptor 3 as a therapeutic target in multiple myeloma.

Paterson JL, Li Z, Wen XY, Masih-Khan E, Chang H, Pollett JB, Trudel S, Stewart AK. Paterson JL, et al. Among authors: trudel s. Br J Haematol. 2004 Mar;124(5):595-603. doi: 10.1111/j.1365-2141.2004.04814.x. Br J Haematol. 2004. PMID: 14871245 Free article.

8

The Bcl-2 family protein inhibitor, ABT-737, has substantial antimyeloma activity and shows synergistic effect with dexamethasone and melphalan.

Trudel S, Stewart AK, Li Z, Shu Y, Liang SB, Trieu Y, Reece D, Paterson J, Wang D, Wen XY. Trudel S, et al. Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):621-9. doi: 10.1158/1078-0432.CCR-06-1526. Clin Cancer Res. 2007. PMID: 17255285

9

A phase I single-agent study of twice-weekly consecutive-day dosing of the proteasome inhibitor carfilzomib in patients with relapsed or refractory multiple myeloma or lymphoma.

Alsina M, Trudel S, Furman RR, Rosen PJ, O'Connor OA, Comenzo RL, Wong A, Kunkel LA, Molineaux CJ, Goy A. Alsina M, et al. Among authors: trudel s. Clin Cancer Res. 2012 Sep 1;18(17):4830-40. doi: 10.1158/1078-0432.CCR-11-3007. Epub 2012 Jul 3. Clin Cancer Res. 2012. PMID: 22761464 Clinical Trial.

10

TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding.

Petrova PS, Viller NN, Wong M, Pang X, Lin GH, Dodge K, Chai V, Chen H, Lee V, House V, Vigo NT, Jin D, Mutukura T, Charbonneau M, Truong T, Viau S, Johnson LD, Linderoth E, Sievers EL, Maleki Vareki S, Figueredo R, Pampillo M, Koropatnick J, Trudel S, Mbong N, Jin L, Wang JC, Uger RA. Petrova PS, et al. Among authors: trudel s. Clin Cancer Res. 2017 Feb 15;23(4):1068-1079. doi: 10.1158/1078-0432.CCR-16-1700. Epub 2016 Nov 17. Clin Cancer Res. 2017. PMID: 27856600

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