Rock DA - Search Results

1

Enzyme source effects on CYP2C9 kinetics and inhibition.

Kumar V, Rock DA, Warren CJ, Tracy TS, Wahlstrom JL. Kumar V, et al. Among authors: rock da. Drug Metab Dispos. 2006 Nov;34(11):1903-8. doi: 10.1124/dmd.106.010249. Epub 2006 Aug 23. Drug Metab Dispos. 2006. PMID: 16928789 Free PMC article.

2

CYP2C9 genotype-dependent effects on in vitro drug-drug interactions: switching of benzbromarone effect from inhibition to activation in the CYP2C9.3 variant.

Hummel MA, Locuson CW, Gannett PM, Rock DA, Mosher CM, Rettie AE, Tracy TS. Hummel MA, et al. Among authors: rock da. Mol Pharmacol. 2005 Sep;68(3):644-51. doi: 10.1124/mol.105.013763. Epub 2005 Jun 13. Mol Pharmacol. 2005. PMID: 15955872

3

Influence of fluorescent probe size and cytochrome b5 on drug-drug interactions in CYP2C9.

Hummel MA, Tracy TS, Hutzler JM, Wahlstrom JL, Zhou Y, Rock DA. Hummel MA, et al. Among authors: rock da. J Biomol Screen. 2006 Apr;11(3):303-9. doi: 10.1177/1087057105285612. Epub 2006 Feb 20. J Biomol Screen. 2006. PMID: 16490777

4

CYP2C9 inhibition: impact of probe selection and pharmacogenetics on in vitro inhibition profiles.

Kumar V, Wahlstrom JL, Rock DA, Warren CJ, Gorman LA, Tracy TS. Kumar V, et al. Among authors: rock da. Drug Metab Dispos. 2006 Dec;34(12):1966-75. doi: 10.1124/dmd.106.010926. Epub 2006 Sep 8. Drug Metab Dispos. 2006. PMID: 16963489

5

Evaluation of CYP2C8 inhibition in vitro: utility of montelukast as a selective CYP2C8 probe substrate.

VandenBrink BM, Foti RS, Rock DA, Wienkers LC, Wahlstrom JL. VandenBrink BM, et al. Among authors: rock da. Drug Metab Dispos. 2011 Sep;39(9):1546-54. doi: 10.1124/dmd.111.039065. Epub 2011 Jun 22. Drug Metab Dispos. 2011. PMID: 21697463

6

A new class of CYP2C9 inhibitors: probing 2C9 specificity with high-affinity benzbromarone derivatives.

Locuson CW 2nd, Wahlstrom JL, Rock DA, Rock DA, Jones JP. Locuson CW 2nd, et al. Among authors: rock da. Drug Metab Dispos. 2003 Jul;31(7):967-71. doi: 10.1124/dmd.31.7.967. Drug Metab Dispos. 2003. PMID: 12814975

7

In vitro inhibition of multiple cytochrome P450 isoforms by xanthone derivatives from mangosteen extract.

Foti RS, Pearson JT, Rock DA, Wahlstrom JL, Wienkers LC. Foti RS, et al. Among authors: rock da. Drug Metab Dispos. 2009 Sep;37(9):1848-55. doi: 10.1124/dmd.109.028043. Epub 2009 Jun 18. Drug Metab Dispos. 2009. PMID: 19541824

8

Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation.

Foti RS, Rock DA, Wienkers LC, Wahlstrom JL. Foti RS, et al. Among authors: rock da. Drug Metab Dispos. 2010 Jun;38(6):981-7. doi: 10.1124/dmd.110.032094. Epub 2010 Mar 4. Drug Metab Dispos. 2010. PMID: 20203109

9

Prediction of CYP2D6 drug interactions from in vitro data: evidence for substrate-dependent inhibition.

VandenBrink BM, Foti RS, Rock DA, Wienkers LC, Wahlstrom JL. VandenBrink BM, et al. Among authors: rock da. Drug Metab Dispos. 2012 Jan;40(1):47-53. doi: 10.1124/dmd.111.041210. Epub 2011 Oct 5. Drug Metab Dispos. 2012. PMID: 21976621

10

Predicting the drug interaction potential of AMG 853, a dual antagonist of the D-prostanoid and chemoattractant receptor-homologous molecule expressed on T helper 2 cells receptors.

Foti RS, Pearson JT, Wong SL, Zalikowski JA, Boudreaux MD, Prokop SP, Davis JA, Banfield C, Emery MG, Rock DA, Wahlstrom JL, Wienkers LC, Amore BM. Foti RS, et al. Among authors: rock da. Drug Metab Dispos. 2012 Dec;40(12):2239-49. doi: 10.1124/dmd.112.047928. Epub 2012 Aug 28. Drug Metab Dispos. 2012. PMID: 22930276

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