Tracy TS - Search Results

1

Enzyme source effects on CYP2C9 kinetics and inhibition.

Kumar V, Rock DA, Warren CJ, Tracy TS, Wahlstrom JL. Kumar V, et al. Among authors: tracy ts. Drug Metab Dispos. 2006 Nov;34(11):1903-8. doi: 10.1124/dmd.106.010249. Epub 2006 Aug 23. Drug Metab Dispos. 2006. PMID: 16928789 Free PMC article.

2

CYP2C9 genotype-dependent effects on in vitro drug-drug interactions: switching of benzbromarone effect from inhibition to activation in the CYP2C9.3 variant.

Hummel MA, Locuson CW, Gannett PM, Rock DA, Mosher CM, Rettie AE, Tracy TS. Hummel MA, et al. Among authors: tracy ts. Mol Pharmacol. 2005 Sep;68(3):644-51. doi: 10.1124/mol.105.013763. Epub 2005 Jun 13. Mol Pharmacol. 2005. PMID: 15955872

3

Influence of fluorescent probe size and cytochrome b5 on drug-drug interactions in CYP2C9.

Hummel MA, Tracy TS, Hutzler JM, Wahlstrom JL, Zhou Y, Rock DA. Hummel MA, et al. Among authors: tracy ts. J Biomol Screen. 2006 Apr;11(3):303-9. doi: 10.1177/1087057105285612. Epub 2006 Feb 20. J Biomol Screen. 2006. PMID: 16490777

4

Amiodarone analog-dependent effects on CYP2C9-mediated metabolism and kinetic profiles.

Kumar V, Locuson CW, Sham YY, Tracy TS. Kumar V, et al. Among authors: tracy ts. Drug Metab Dispos. 2006 Oct;34(10):1688-96. doi: 10.1124/dmd.106.010678. Epub 2006 Jun 30. Drug Metab Dispos. 2006. PMID: 16815961

5

CYP2C9 inhibition: impact of probe selection and pharmacogenetics on in vitro inhibition profiles.

Kumar V, Wahlstrom JL, Rock DA, Warren CJ, Gorman LA, Tracy TS. Kumar V, et al. Among authors: tracy ts. Drug Metab Dispos. 2006 Dec;34(12):1966-75. doi: 10.1124/dmd.106.010926. Epub 2006 Sep 8. Drug Metab Dispos. 2006. PMID: 16963489

6

Differential genotype dependent inhibition of CYP2C9 in humans.

Kumar V, Brundage RC, Oetting WS, Leppik IE, Tracy TS. Kumar V, et al. Among authors: tracy ts. Drug Metab Dispos. 2008 Jul;36(7):1242-8. doi: 10.1124/dmd.108.020396. Epub 2008 Mar 31. Drug Metab Dispos. 2008. PMID: 18378563 Free PMC article. Clinical Trial.

7

CYP2C9 protein interactions with cytochrome b(5): effects on the coupling of catalysis.

Locuson CW, Wienkers LC, Jones JP, Tracy TS. Locuson CW, et al. Among authors: tracy ts. Drug Metab Dispos. 2007 Jul;35(7):1174-81. doi: 10.1124/dmd.107.014910. Epub 2007 Apr 19. Drug Metab Dispos. 2007. PMID: 17446262 Free PMC article.

8

Mechanism-based inactivation of cytochrome P450 2C9 by tienilic acid and (+/-)-suprofen: a comparison of kinetics and probe substrate selection.

Hutzler JM, Balogh LM, Zientek M, Kumar V, Tracy TS. Hutzler JM, et al. Among authors: tracy ts. Drug Metab Dispos. 2009 Jan;37(1):59-65. doi: 10.1124/dmd.108.023358. Epub 2008 Oct 6. Drug Metab Dispos. 2009. PMID: 18838506 Free PMC article.

9

CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus.

Subramanian M, Tam H, Zheng H, Tracy TS. Subramanian M, et al. Among authors: tracy ts. Drug Metab Dispos. 2010 Jun;38(6):1003-9. doi: 10.1124/dmd.109.030155. Epub 2010 Mar 9. Drug Metab Dispos. 2010. PMID: 20215413 Free PMC article.

10

Development of an in vitro system with human liver microsomes for phenotyping of CYP2C9 genetic polymorphisms with a mechanism-based inactivator.

Flora DR, Tracy TS. Flora DR, et al. Among authors: tracy ts. Drug Metab Dispos. 2012 Apr;40(4):836-42. doi: 10.1124/dmd.111.043372. Epub 2011 Dec 28. Drug Metab Dispos. 2012. PMID: 22205778 Free PMC article.

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