Wideman RD - Search Results

1

Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1).

Wideman RD, Yu IL, Webber TD, Verchere CB, Johnson JD, Cheung AT, Kieffer TJ. Wideman RD, et al. Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13468-73. doi: 10.1073/pnas.0600655103. Epub 2006 Aug 28. Proc Natl Acad Sci U S A. 2006. PMID: 16938896 Free PMC article.

2

A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice.

Wideman RD, Covey SD, Webb GC, Drucker DJ, Kieffer TJ. Wideman RD, et al. Diabetes. 2007 Nov;56(11):2744-52. doi: 10.2337/db07-0563. Epub 2007 Aug 13. Diabetes. 2007. PMID: 17698597

3

Transplantation of PC1/3-Expressing alpha-cells improves glucose handling and cold tolerance in leptin-resistant mice.

Wideman RD, Gray SL, Covey SD, Webb GC, Kieffer TJ. Wideman RD, et al. Mol Ther. 2009 Jan;17(1):191-8. doi: 10.1038/mt.2008.219. Epub 2008 Oct 21. Mol Ther. 2009. PMID: 18941442 Free PMC article.

4

Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion.

Fujita Y, Wideman RD, Asadi A, Yang GK, Baker R, Webber T, Zhang T, Wang R, Ao Z, Warnock GL, Kwok YN, Kieffer TJ. Fujita Y, et al. Among authors: wideman rd. Gastroenterology. 2010 May;138(5):1966-75. doi: 10.1053/j.gastro.2010.01.049. Epub 2010 Feb 4. Gastroenterology. 2010. PMID: 20138041

5

Glucose-dependent insulinotropic polypeptide as a regulator of beta cell function and fate.

Wideman RD, Kieffer TJ. Wideman RD, et al. Horm Metab Res. 2004 Nov-Dec;36(11-12):782-6. doi: 10.1055/s-2004-826164. Horm Metab Res. 2004. PMID: 15655709 Review.

6

The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

Covey SD, Wideman RD, McDonald C, Unniappan S, Huynh F, Asadi A, Speck M, Webber T, Chua SC, Kieffer TJ. Covey SD, et al. Among authors: wideman rd. Cell Metab. 2006 Oct;4(4):291-302. doi: 10.1016/j.cmet.2006.09.005. Cell Metab. 2006. PMID: 17011502 Free article.

7

Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo.

Fujita Y, Wideman RD, Speck M, Asadi A, King DS, Webber TD, Haneda M, Kieffer TJ. Fujita Y, et al. Among authors: wideman rd. Am J Physiol Endocrinol Metab. 2009 Mar;296(3):E473-9. doi: 10.1152/ajpendo.90636.2008. Epub 2008 Dec 23. Am J Physiol Endocrinol Metab. 2009. PMID: 19106249 Free article.

8

Treatment of diabetes by transplantation of drug-inducible insulin-producing gut cells.

Unniappan S, Wideman RD, Donald C, Gunn V, Wall JL, Zhang QX, Webber TD, Cheung AT, Kieffer TJ. Unniappan S, et al. Among authors: wideman rd. J Mol Med (Berl). 2009 Jul;87(7):703-12. doi: 10.1007/s00109-009-0465-0. Epub 2009 Apr 23. J Mol Med (Berl). 2009. PMID: 19387601

9

Mining incretin hormone pathways for novel therapies.

Wideman RD, Kieffer TJ. Wideman RD, et al. Trends Endocrinol Metab. 2009 Aug;20(6):280-6. doi: 10.1016/j.tem.2009.02.005. Trends Endocrinol Metab. 2009. PMID: 19595611 Review.

10

Cellular reprogramming of human amniotic fluid cells to express insulin.

Gage BK, Riedel MJ, Karanu F, Rezania A, Fujita Y, Webber TD, Baker RK, Wideman RD, Kieffer TJ. Gage BK, et al. Among authors: wideman rd. Differentiation. 2010 Sep-Oct;80(2-3):130-9. doi: 10.1016/j.diff.2010.05.007. Epub 2010 Jun 19. Differentiation. 2010. PMID: 20561745

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