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Sirolimus-induced vascular dysfunction. Increased mitochondrial and nicotinamide adenosine dinucleotide phosphate oxidase-dependent superoxide production and decreased vascular nitric oxide formation.
Jabs A, Göbel S, Wenzel P, Kleschyov AL, Hortmann M, Oelze M, Daiber A, Münzel T. Jabs A, et al. Among authors: hortmann m. J Am Coll Cardiol. 2008 Jun 3;51(22):2130-8. doi: 10.1016/j.jacc.2008.01.058. J Am Coll Cardiol. 2008. PMID: 18510959 Free article.
First evidence for a crosstalk between mitochondrial and NADPH oxidase-derived reactive oxygen species in nitroglycerin-triggered vascular dysfunction.
Wenzel P, Mollnau H, Oelze M, Schulz E, Wickramanayake JM, Müller J, Schuhmacher S, Hortmann M, Baldus S, Gori T, Brandes RP, Münzel T, Daiber A. Wenzel P, et al. Among authors: hortmann m. Antioxid Redox Signal. 2008 Aug;10(8):1435-47. doi: 10.1089/ars.2007.1969. Antioxid Redox Signal. 2008. PMID: 18522491
Cyclooxygenase 2-selective and nonselective nonsteroidal anti-inflammatory drugs induce oxidative stress by up-regulating vascular NADPH oxidases.
Li H, Hortmann M, Daiber A, Oelze M, Ostad MA, Schwarz PM, Xu H, Xia N, Kleschyov AL, Mang C, Warnholtz A, Münzel T, Förstermann U. Li H, et al. Among authors: hortmann m. J Pharmacol Exp Ther. 2008 Sep;326(3):745-53. doi: 10.1124/jpet.108.139030. Epub 2008 Jun 11. J Pharmacol Exp Ther. 2008. PMID: 18550689
Pentaerythritol tetranitrate improves angiotensin II-induced vascular dysfunction via induction of heme oxygenase-1.
Schuhmacher S, Wenzel P, Schulz E, Oelze M, Mang C, Kamuf J, Gori T, Jansen T, Knorr M, Karbach S, Hortmann M, Mäthner F, Bhatnagar A, Förstermann U, Li H, Münzel T, Daiber A. Schuhmacher S, et al. Among authors: hortmann m. Hypertension. 2010 Apr;55(4):897-904. doi: 10.1161/HYPERTENSIONAHA.109.149542. Epub 2010 Feb 15. Hypertension. 2010. PMID: 20157049 Free PMC article.
α1AMP-activated protein kinase preserves endothelial function during chronic angiotensin II treatment by limiting Nox2 upregulation.
Schuhmacher S, Foretz M, Knorr M, Jansen T, Hortmann M, Wenzel P, Oelze M, Kleschyov AL, Daiber A, Keaney JF Jr, Wegener G, Lackner K, Münzel T, Viollet B, Schulz E. Schuhmacher S, et al. Among authors: hortmann m. Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):560-6. doi: 10.1161/ATVBAHA.110.219543. Epub 2011 Jan 4. Arterioscler Thromb Vasc Biol. 2011. PMID: 21205985 Free PMC article.
35 results