Morgan RA - Search Results

1

Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability.

Cohen CJ, Zhao Y, Zheng Z, Rosenberg SA, Morgan RA. Cohen CJ, et al. Among authors: morgan ra. Cancer Res. 2006 Sep 1;66(17):8878-86. doi: 10.1158/0008-5472.CAN-06-1450. Cancer Res. 2006. PMID: 16951205 Free PMC article.

2

Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes.

Jones S, Peng PD, Yang S, Hsu C, Cohen CJ, Zhao Y, Abad J, Zheng Z, Rosenberg SA, Morgan RA. Jones S, et al. Among authors: morgan ra. Hum Gene Ther. 2009 Jun;20(6):630-40. doi: 10.1089/hum.2008.048. Hum Gene Ther. 2009. PMID: 19265475 Free PMC article.

3

Lack of specific gamma-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation.

Burns WR, Zheng Z, Rosenberg SA, Morgan RA. Burns WR, et al. Among authors: morgan ra. Blood. 2009 Oct 1;114(14):2888-99. doi: 10.1182/blood-2009-01-199216. Epub 2009 Jul 9. Blood. 2009. PMID: 19589923 Free PMC article.

4

A herceptin-based chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity.

Zhao Y, Wang QJ, Yang S, Kochenderfer JN, Zheng Z, Zhong X, Sadelain M, Eshhar Z, Rosenberg SA, Morgan RA. Zhao Y, et al. Among authors: morgan ra. J Immunol. 2009 Nov 1;183(9):5563-74. doi: 10.4049/jimmunol.0900447. J Immunol. 2009. PMID: 19843940 Free PMC article.

5

A high molecular weight melanoma-associated antigen-specific chimeric antigen receptor redirects lymphocytes to target human melanomas.

Burns WR, Zhao Y, Frankel TL, Hinrichs CS, Zheng Z, Xu H, Feldman SA, Ferrone S, Rosenberg SA, Morgan RA. Burns WR, et al. Among authors: morgan ra. Cancer Res. 2010 Apr 15;70(8):3027-33. doi: 10.1158/0008-5472.CAN-09-2824. Cancer Res. 2010. PMID: 20395199 Free PMC article.

6

A simplified method for the clinical-scale generation of central memory-like CD8+ T cells after transduction with lentiviral vectors encoding antitumor antigen T-cell receptors.

Yang S, Dudley ME, Rosenberg SA, Morgan RA. Yang S, et al. Among authors: morgan ra. J Immunother. 2010 Jul-Aug;33(6):648-58. doi: 10.1097/CJI.0b013e3181e311cb. J Immunother. 2010. PMID: 20551831 Free PMC article.

7

Enhanced receptor expression and in vitro effector function of a murine-human hybrid MART-1-reactive T cell receptor following a rapid expansion.

Goff SL, Johnson LA, Black MA, Xu H, Zheng Z, Cohen CJ, Morgan RA, Rosenberg SA, Feldman SA. Goff SL, et al. Among authors: morgan ra. Cancer Immunol Immunother. 2010 Oct;59(10):1551-60. doi: 10.1007/s00262-010-0882-5. Epub 2010 Jul 14. Cancer Immunol Immunother. 2010. PMID: 20628878 Free PMC article.

8

Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts.

Kerkar SP, Muranski P, Kaiser A, Boni A, Sanchez-Perez L, Yu Z, Palmer DC, Reger RN, Borman ZA, Zhang L, Morgan RA, Gattinoni L, Rosenberg SA, Trinchieri G, Restifo NP. Kerkar SP, et al. Among authors: morgan ra. Cancer Res. 2010 Sep 1;70(17):6725-34. doi: 10.1158/0008-5472.CAN-10-0735. Epub 2010 Jul 20. Cancer Res. 2010. PMID: 20647327 Free PMC article.

9

Adoptive cell therapy: genetic modification to redirect effector cell specificity.

Morgan RA, Dudley ME, Rosenberg SA. Morgan RA, et al. Cancer J. 2010 Jul-Aug;16(4):336-41. doi: 10.1097/PPO.0b013e3181eb3879. Cancer J. 2010. PMID: 20693844 Free PMC article. Review.

10

Development of human anti-murine T-cell receptor antibodies in both responding and nonresponding patients enrolled in TCR gene therapy trials.

Davis JL, Theoret MR, Zheng Z, Lamers CH, Rosenberg SA, Morgan RA. Davis JL, et al. Among authors: morgan ra. Clin Cancer Res. 2010 Dec 1;16(23):5852-61. doi: 10.1158/1078-0432.CCR-10-1280. Clin Cancer Res. 2010. PMID: 21138872 Free PMC article. Clinical Trial.

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