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Page 1
Humanization of yeast to produce complex terminally sialylated glycoproteins.
Hamilton SR, Davidson RC, Sethuraman N, Nett JH, Jiang Y, Rios S, Bobrowicz P, Stadheim TA, Li H, Choi BK, Hopkins D, Wischnewski H, Roser J, Mitchell T, Strawbridge RR, Hoopes J, Wildt S, Gerngross TU. Hamilton SR, et al. Science. 2006 Sep 8;313(5792):1441-3. doi: 10.1126/science.1130256. Science. 2006. PMID: 16960007
Production of complex human glycoproteins in yeast.
Hamilton SR, Bobrowicz P, Bobrowicz B, Davidson RC, Li H, Mitchell T, Nett JH, Rausch S, Stadheim TA, Wischnewski H, Wildt S, Gerngross TU. Hamilton SR, et al. Science. 2003 Aug 29;301(5637):1244-6. doi: 10.1126/science.1088166. Science. 2003. PMID: 12947202
Engineering of an artificial glycosylation pathway blocked in core oligosaccharide assembly in the yeast Pichia pastoris: production of complex humanized glycoproteins with terminal galactose.
Bobrowicz P, Davidson RC, Li H, Potgieter TI, Nett JH, Hamilton SR, Stadheim TA, Miele RG, Bobrowicz B, Mitchell T, Rausch S, Renfer E, Wildt S. Bobrowicz P, et al. Among authors: hamilton sr. Glycobiology. 2004 Sep;14(9):757-66. doi: 10.1093/glycob/cwh104. Epub 2004 Jun 9. Glycobiology. 2004. PMID: 15190003
Optimization of humanized IgGs in glycoengineered Pichia pastoris.
Li H, Sethuraman N, Stadheim TA, Zha D, Prinz B, Ballew N, Bobrowicz P, Choi BK, Cook WJ, Cukan M, Houston-Cummings NR, Davidson R, Gong B, Hamilton SR, Hoopes JP, Jiang Y, Kim N, Mansfield R, Nett JH, Rios S, Strawbridge R, Wildt S, Gerngross TU. Li H, et al. Among authors: hamilton sr. Nat Biotechnol. 2006 Feb;24(2):210-5. doi: 10.1038/nbt1178. Epub 2006 Jan 22. Nat Biotechnol. 2006. PMID: 16429149
Production of sialylated O-linked glycans in Pichia pastoris.
Hamilton SR, Cook WJ, Gomathinayagam S, Burnina I, Bukowski J, Hopkins D, Schwartz S, Du M, Sharkey NJ, Bobrowicz P, Wildt S, Li H, Stadheim TA, Nett JH. Hamilton SR, et al. Glycobiology. 2013 Oct;23(10):1192-203. doi: 10.1093/glycob/cwt056. Epub 2013 Jul 26. Glycobiology. 2013. PMID: 23893788
Binding of DC-SIGN to glycoproteins expressed in glycoengineered Pichia pastoris.
Cukan MC, Hopkins D, Burnina I, Button M, Giaccone E, Houston-Cummings NR, Jiang Y, Li F, Mallem M, Mitchell T, Moore R, Nylen A, Prinz B, Rios S, Sharkey N, Zha D, Hamilton S, Li H, Stadheim TA. Cukan MC, et al. J Immunol Methods. 2012 Dec 14;386(1-2):34-42. doi: 10.1016/j.jim.2012.08.015. Epub 2012 Sep 14. J Immunol Methods. 2012. PMID: 22982058
Intact {alpha}-1,2-endomannosidase is a typical type II membrane protein.
Hamilton SR, Li H, Wischnewski H, Prasad A, Kerley-Hamilton JS, Mitchell T, Walling AJ, Davidson RC, Wildt S, Gerngross TU. Hamilton SR, et al. Glycobiology. 2005 Jun;15(6):615-24. doi: 10.1093/glycob/cwi045. Epub 2005 Jan 26. Glycobiology. 2005. PMID: 15677381
480 results