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A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia.
Majewski IJ, Metcalf D, Mielke LA, Krebs DL, Ellis S, Carpinelli MR, Mifsud S, Di Rago L, Corbin J, Nicola NA, Hilton DJ, Alexander WS. Majewski IJ, et al. Among authors: metcalf d. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14146-51. doi: 10.1073/pnas.0606439103. Epub 2006 Sep 11. Proc Natl Acad Sci U S A. 2006. PMID: 16966598 Free PMC article.
Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling.
Carpinelli MR, Hilton DJ, Metcalf D, Antonchuk JL, Hyland CD, Mifsud SL, Di Rago L, Hilton AA, Willson TA, Roberts AW, Ramsay RG, Nicola NA, Alexander WS. Carpinelli MR, et al. Among authors: metcalf d. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6553-8. doi: 10.1073/pnas.0401496101. Epub 2004 Apr 7. Proc Natl Acad Sci U S A. 2004. PMID: 15071178 Free PMC article.
Development of hydrocephalus in mice lacking SOCS7.
Krebs DL, Metcalf D, Merson TD, Voss AK, Thomas T, Zhang JG, Rakar S, O'bryan MK, Willson TA, Viney EM, Mielke LA, Nicola NA, Hilton DJ, Alexander WS. Krebs DL, et al. Among authors: metcalf d. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15446-51. doi: 10.1073/pnas.0406870101. Epub 2004 Oct 19. Proc Natl Acad Sci U S A. 2004. PMID: 15494444 Free PMC article.
777 results