Beckman RA - Search Results

1

Efficiency of carcinogenesis with and without a mutator mutation.

Beckman RA, Loeb LA. Beckman RA, et al. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14140-5. doi: 10.1073/pnas.0606271103. Epub 2006 Sep 11. Proc Natl Acad Sci U S A. 2006. PMID: 16966602 Free PMC article.

2

Genetic instability in cancer: theory and experiment.

Beckman RA, Loeb LA. Beckman RA, et al. Semin Cancer Biol. 2005 Dec;15(6):423-35. doi: 10.1016/j.semcancer.2005.06.007. Semin Cancer Biol. 2005. PMID: 16043359 Review.

3

Negative clonal selection in tumor evolution.

Beckman RA, Loeb LA. Beckman RA, et al. Genetics. 2005 Dec;171(4):2123-31. doi: 10.1534/genetics.105.040840. Epub 2005 Sep 2. Genetics. 2005. PMID: 16143627 Free PMC article.

4

Cancers exhibit a mutator phenotype: clinical implications.

Loeb LA, Bielas JH, Beckman RA. Loeb LA, et al. Among authors: beckman ra. Cancer Res. 2008 May 15;68(10):3551-7; discussion 3557. doi: 10.1158/0008-5472.CAN-07-5835. Cancer Res. 2008. PMID: 18483233 Review.

5

Evolutionary dynamics and significance of multiple subclonal mutations in cancer.

Beckman RA, Loeb LA. Beckman RA, et al. DNA Repair (Amst). 2017 Aug;56:7-15. doi: 10.1016/j.dnarep.2017.06.002. Epub 2017 Jun 9. DNA Repair (Amst). 2017. PMID: 28652129 Free PMC article. Review.

6

Extensive subclonal mutational diversity in human colorectal cancer and its significance.

Loeb LA, Kohrn BF, Loubet-Senear KJ, Dunn YJ, Ahn EH, O'Sullivan JN, Salk JJ, Bronner MP, Beckman RA. Loeb LA, et al. Among authors: beckman ra. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26863-26872. doi: 10.1073/pnas.1910301116. Epub 2019 Dec 5. Proc Natl Acad Sci U S A. 2019. PMID: 31806761 Free PMC article.

7

Multi-stage proofreading in DNA replication.

Beckman RA, Loeb LA. Beckman RA, et al. Q Rev Biophys. 1993 Aug;26(3):225-331. doi: 10.1017/s0033583500002869. Q Rev Biophys. 1993. PMID: 8022969 Review.

8

Rare Mutations in Cancer Drug Resistance and Implications for Therapy.

Beckman RA, Loeb LA. Beckman RA, et al. Clin Pharmacol Ther. 2020 Sep;108(3):437-439. doi: 10.1002/cpt.1938. Epub 2020 Jul 10. Clin Pharmacol Ther. 2020. PMID: 32648584 Free PMC article. No abstract available.

9

Efficiency of carcinogenesis: is the mutator phenotype inevitable?

Beckman RA. Beckman RA. Semin Cancer Biol. 2010 Oct;20(5):340-52. doi: 10.1016/j.semcancer.2010.10.004. Epub 2010 Oct 8. Semin Cancer Biol. 2010. PMID: 20934514 Review.

10

On the fidelity of DNA replication: manganese mutagenesis in vitro.

Beckman RA, Mildvan AS, Loeb LA. Beckman RA, et al. Biochemistry. 1985 Oct 8;24(21):5810-7. doi: 10.1021/bi00342a019. Biochemistry. 1985. PMID: 3910084

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