Johnson AA - Search Results

1

Covalent binding of the natural antimicrobial peptide indolicidin to DNA abasic sites.

Marchand C, Krajewski K, Lee HF, Antony S, Johnson AA, Amin R, Roller P, Kvaratskhelia M, Pommier Y. Marchand C, et al. Among authors: johnson aa. Nucleic Acids Res. 2006;34(18):5157-65. doi: 10.1093/nar/gkl667. Epub 2006 Sep 22. Nucleic Acids Res. 2006. PMID: 16998183 Free PMC article.

2

Probing HIV-1 integrase inhibitor binding sites with position-specific integrase-DNA cross-linking assays.

Johnson AA, Marchand C, Patil SS, Costi R, Di Santo R, Burke TR Jr, Pommier Y. Johnson AA, et al. Mol Pharmacol. 2007 Mar;71(3):893-901. doi: 10.1124/mol.106.030817. Epub 2006 Dec 15. Mol Pharmacol. 2007. PMID: 17172465

3

Metal-dependent inhibition of HIV-1 integrase by beta-diketo acids and resistance of the soluble double-mutant (F185K/C280S).

Marchand C, Johnson AA, Karki RG, Pais GC, Zhang X, Cowansage K, Patel TA, Nicklaus MC, Burke TR Jr, Pommier Y. Marchand C, et al. Among authors: johnson aa. Mol Pharmacol. 2003 Sep;64(3):600-9. doi: 10.1124/mol.64.3.600. Mol Pharmacol. 2003. PMID: 12920196

4

Position-specific suppression and enhancement of HIV-1 integrase reactions by minor groove benzo[a]pyrene diol epoxide deoxyguanine adducts: implications for molecular interactions between integrase and substrates.

Johnson AA, Sayer JM, Yagi H, Kalena GP, Amin R, Jerina DM, Pommier Y. Johnson AA, et al. J Biol Chem. 2004 Feb 27;279(9):7947-55. doi: 10.1074/jbc.M311263200. Epub 2003 Nov 18. J Biol Chem. 2004. PMID: 14627697 Free article.

5

HIV-1 integrase inhibitors: a decade of research and two drugs in clinical trial.

Johnson AA, Marchand C, Pommier Y. Johnson AA, et al. Curr Top Med Chem. 2004;4(10):1059-77. doi: 10.2174/1568026043388394. Curr Top Med Chem. 2004. PMID: 15193139 Review.

6

Integrase inhibitors to treat HIV/AIDS.

Pommier Y, Johnson AA, Marchand C. Pommier Y, et al. Among authors: johnson aa. Nat Rev Drug Discov. 2005 Mar;4(3):236-48. doi: 10.1038/nrd1660. Nat Rev Drug Discov. 2005. PMID: 15729361 Review.

7

Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop.

Johnson AA, Santos W, Pais GC, Marchand C, Amin R, Burke TR Jr, Verdine G, Pommier Y. Johnson AA, et al. J Biol Chem. 2006 Jan 6;281(1):461-7. doi: 10.1074/jbc.M511348200. Epub 2005 Oct 27. J Biol Chem. 2006. PMID: 16257967 Free article.

8

Preferential inhibition of the magnesium-dependent strand transfer reaction of HIV-1 integrase by alpha-hydroxytropolones.

Semenova EA, Johnson AA, Marchand C, Davis DA, Yarchoan R, Pommier Y. Semenova EA, et al. Among authors: johnson aa. Mol Pharmacol. 2006 Apr;69(4):1454-60. doi: 10.1124/mol.105.020321. Epub 2006 Jan 17. Mol Pharmacol. 2006. PMID: 16418335

9

Integration of human immunodeficiency virus as a target for antiretroviral therapy.

Semenova EA, Johnson AA, Marchand C, Pommier Y. Semenova EA, et al. Among authors: johnson aa. Curr Opin HIV AIDS. 2006 Sep;1(5):380-7. doi: 10.1097/01.COH.0000239850.14991.f9. Curr Opin HIV AIDS. 2006. PMID: 19372837

10

Mechanisms and inhibition of HIV integration.

Marchand C, Johnson AA, Semenova E, Pommier Y. Marchand C, et al. Among authors: johnson aa. Drug Discov Today Dis Mech. 2006 Jul 1;3(2):253-260. doi: 10.1016/j.ddmec.2006.05.004. Drug Discov Today Dis Mech. 2006. PMID: 20431697 Free PMC article.

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