Kvaratskhelia M - Search Results

1

Covalent binding of the natural antimicrobial peptide indolicidin to DNA abasic sites.

Marchand C, Krajewski K, Lee HF, Antony S, Johnson AA, Amin R, Roller P, Kvaratskhelia M, Pommier Y. Marchand C, et al. Among authors: kvaratskhelia m. Nucleic Acids Res. 2006;34(18):5157-65. doi: 10.1093/nar/gkl667. Epub 2006 Sep 22. Nucleic Acids Res. 2006. PMID: 16998183 Free PMC article.

2

Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity.

Wendeler M, Lee HF, Bermingham A, Miller JT, Chertov O, Bona MK, Baichoo NS, Ehteshami M, Beutler J, O'Keefe BR, Götte M, Kvaratskhelia M, Le Grice S. Wendeler M, et al. Among authors: kvaratskhelia m. ACS Chem Biol. 2008 Oct 17;3(10):635-44. doi: 10.1021/cb8001039. Epub 2008 Oct 3. ACS Chem Biol. 2008. PMID: 18831589 Free PMC article.

3

Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates.

Ditzler MA, Bose D, Shkriabai N, Marchand B, Sarafianos SG, Kvaratskhelia M, Burke DH. Ditzler MA, et al. Among authors: kvaratskhelia m. Nucleic Acids Res. 2011 Oct;39(18):8237-47. doi: 10.1093/nar/gkr381. Epub 2011 Jul 3. Nucleic Acids Res. 2011. PMID: 21727088 Free PMC article.

4

FRET analysis reveals distinct conformations of IN tetramers in the presence of viral DNA or LEDGF/p75.

Kessl JJ, Li M, Ignatov M, Shkriabai N, Eidahl JO, Feng L, Musier-Forsyth K, Craigie R, Kvaratskhelia M. Kessl JJ, et al. Among authors: kvaratskhelia m. Nucleic Acids Res. 2011 Nov 1;39(20):9009-22. doi: 10.1093/nar/gkr581. Epub 2011 Jul 19. Nucleic Acids Res. 2011. PMID: 21771857 Free PMC article.

5

HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor.

Wang H, Jurado KA, Wu X, Shun MC, Li X, Ferris AL, Smith SJ, Patel PA, Fuchs JR, Cherepanov P, Kvaratskhelia M, Hughes SH, Engelman A. Wang H, et al. Among authors: kvaratskhelia m. Nucleic Acids Res. 2012 Dec;40(22):11518-30. doi: 10.1093/nar/gks913. Epub 2012 Oct 5. Nucleic Acids Res. 2012. PMID: 23042676 Free PMC article.

6

HIV-1 Integrase-Targeted Short Peptides Derived from a Viral Protein R Sequence.

Zhao XZ, Métifiot M, Kiselev E, Kessl JJ, Maddali K, Marchand C, Kvaratskhelia M, Pommier Y, Burke TR Jr. Zhao XZ, et al. Among authors: kvaratskhelia m. Molecules. 2018 Jul 26;23(8):1858. doi: 10.3390/molecules23081858. Molecules. 2018. PMID: 30049955 Free PMC article.

7

Identification of specific HIV-1 reverse transcriptase contacts to the viral RNA:tRNA complex by mass spectrometry and a primary amine selective reagent.

Kvaratskhelia M, Miller JT, Budihas SR, Pannell LK, Le Grice SF. Kvaratskhelia M, et al. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):15988-93. doi: 10.1073/pnas.252550199. Epub 2002 Dec 2. Proc Natl Acad Sci U S A. 2002. PMID: 12461175 Free PMC article.

8

Identification of an inhibitor-binding site to HIV-1 integrase with affinity acetylation and mass spectrometry.

Shkriabai N, Patil SS, Hess S, Budihas SR, Craigie R, Burke TR Jr, Le Grice SF, Kvaratskhelia M. Shkriabai N, et al. Among authors: kvaratskhelia m. Proc Natl Acad Sci U S A. 2004 May 4;101(18):6894-9. doi: 10.1073/pnas.0400873101. Epub 2004 Apr 26. Proc Natl Acad Sci U S A. 2004. PMID: 15118107 Free PMC article.

9

An allosteric mechanism for inhibiting HIV-1 integrase with a small molecule.

Kessl JJ, Eidahl JO, Shkriabai N, Zhao Z, McKee CJ, Hess S, Burke TR Jr, Kvaratskhelia M. Kessl JJ, et al. Among authors: kvaratskhelia m. Mol Pharmacol. 2009 Oct;76(4):824-32. doi: 10.1124/mol.109.058883. Epub 2009 Jul 28. Mol Pharmacol. 2009. PMID: 19638533 Free PMC article.

10

Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes.

Eidahl JO, Crowe BL, North JA, McKee CJ, Shkriabai N, Feng L, Plumb M, Graham RL, Gorelick RJ, Hess S, Poirier MG, Foster MP, Kvaratskhelia M. Eidahl JO, et al. Among authors: kvaratskhelia m. Nucleic Acids Res. 2013 Apr 1;41(6):3924-36. doi: 10.1093/nar/gkt074. Epub 2013 Feb 8. Nucleic Acids Res. 2013. PMID: 23396443 Free PMC article.

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