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Pharmacological inhibition of poly(ADP-ribose) polymerase inhibits angiogenesis.
Rajesh M, Mukhopadhyay P, Bátkai S, Godlewski G, Haskó G, Liaudet L, Pacher P. Rajesh M, et al. Among authors: godlewski g. Biochem Biophys Res Commun. 2006 Nov 17;350(2):352-7. doi: 10.1016/j.bbrc.2006.09.049. Epub 2006 Sep 20. Biochem Biophys Res Commun. 2006. PMID: 17007818 Free PMC article.
Poly(ADP-ribose)polymerase inhibition decreases angiogenesis.
Rajesh M, Mukhopadhyay P, Godlewski G, Bátkai S, Haskó G, Liaudet L, Pacher P. Rajesh M, et al. Among authors: godlewski g. Biochem Biophys Res Commun. 2006 Dec 1;350(4):1056-62. doi: 10.1016/j.bbrc.2006.09.160. Epub 2006 Oct 9. Biochem Biophys Res Commun. 2006. PMID: 17046715 Free PMC article.
PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis.
Mukhopadhyay P, Horváth B, Rajesh M, Varga ZV, Gariani K, Ryu D, Cao Z, Holovac E, Park O, Zhou Z, Xu MJ, Wang W, Godlewski G, Paloczi J, Nemeth BT, Persidsky Y, Liaudet L, Haskó G, Bai P, Boulares AH, Auwerx J, Gao B, Pacher P. Mukhopadhyay P, et al. Among authors: godlewski g. J Hepatol. 2017 Mar;66(3):589-600. doi: 10.1016/j.jhep.2016.10.023. Epub 2016 Oct 29. J Hepatol. 2017. PMID: 27984176
The endogenous brain constituent N-arachidonoyl L-serine is an activator of large conductance Ca2+-activated K+ channels.
Godlewski G, Offertáler L, Osei-Hyiaman D, Mo FM, Harvey-White J, Liu J, Davis MI, Zhang L, Razdan RK, Milman G, Pacher P, Mukhopadhyay P, Lovinger DM, Kunos G. Godlewski G, et al. J Pharmacol Exp Ther. 2009 Jan;328(1):351-61. doi: 10.1124/jpet.108.144717. Epub 2008 Oct 15. J Pharmacol Exp Ther. 2009. PMID: 18923087 Free PMC article.
Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy.
Jourdan T, Szanda G, Rosenberg AZ, Tam J, Earley BJ, Godlewski G, Cinar R, Liu Z, Liu J, Ju C, Pacher P, Kunos G. Jourdan T, et al. Among authors: godlewski g. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5420-8. doi: 10.1073/pnas.1419901111. Epub 2014 Nov 24. Proc Natl Acad Sci U S A. 2014. PMID: 25422468 Free PMC article.
Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects.
Godlewski G, Alapafuja SO, Bátkai S, Nikas SP, Cinar R, Offertáler L, Osei-Hyiaman D, Liu J, Mukhopadhyay B, Harvey-White J, Tam J, Pacak K, Blankman JL, Cravatt BF, Makriyannis A, Kunos G. Godlewski G, et al. Chem Biol. 2010 Nov 24;17(11):1256-66. doi: 10.1016/j.chembiol.2010.08.013. Chem Biol. 2010. PMID: 21095576 Free PMC article.
196 results