Johnston JA - Search Results

1

CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover.

Orr SJ, Morgan NM, Elliott J, Burrows JF, Scott CJ, McVicar DW, Johnston JA. Orr SJ, et al. Among authors: johnston ja. Blood. 2007 Feb 1;109(3):1061-8. doi: 10.1182/blood-2006-05-023556. Epub 2006 Sep 28. Blood. 2007. PMID: 17008544 Free article.

2

SOCS3 targets Siglec 7 for proteasomal degradation and blocks Siglec 7-mediated responses.

Orr SJ, Morgan NM, Buick RJ, Boyd CR, Elliott J, Burrows JF, Jefferies CA, Crocker PR, Johnston JA. Orr SJ, et al. Among authors: johnston ja. J Biol Chem. 2007 Feb 9;282(6):3418-22. doi: 10.1074/jbc.C600216200. Epub 2006 Nov 30. J Biol Chem. 2007. PMID: 17138568 Free article.

3

The myeloproliferative disorder-associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3.

Hookham MB, Elliott J, Suessmuth Y, Staerk J, Ward AC, Vainchenker W, Percy MJ, McMullin MF, Constantinescu SN, Johnston JA. Hookham MB, et al. Among authors: johnston ja. Blood. 2007 Jun 1;109(11):4924-9. doi: 10.1182/blood-2006-08-039735. Epub 2007 Feb 22. Blood. 2007. PMID: 17317861 Free article.

4

De-ubiquitinating enzymes: intracellular signalling and disease.

Johnston JA, Burrows JF. Johnston JA, et al. Biochem Soc Trans. 2006 Nov;34(Pt 5):764-9. doi: 10.1042/BST0340764. Biochem Soc Trans. 2006. PMID: 17052193

5

Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation.

Haan S, Ferguson P, Sommer U, Hiremath M, McVicar DW, Heinrich PC, Johnston JA, Cacalano NA. Haan S, et al. Among authors: johnston ja. J Biol Chem. 2003 Aug 22;278(34):31972-9. doi: 10.1074/jbc.M303170200. Epub 2003 Jun 3. J Biol Chem. 2003. PMID: 12783885 Free article.

6

Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligase.

Elliott J, Lynch OT, Suessmuth Y, Qian P, Boyd CR, Burrows JF, Buick R, Stevenson NJ, Touzelet O, Gadina M, Power UF, Johnston JA. Elliott J, et al. Among authors: johnston ja. J Virol. 2007 Apr;81(7):3428-36. doi: 10.1128/JVI.02303-06. Epub 2007 Jan 24. J Virol. 2007. PMID: 17251292 Free PMC article.

7

The suppressors of cytokine signalling E3 ligases behave as tumour suppressors.

Elliott J, Hookham MB, Johnston JA. Elliott J, et al. Among authors: johnston ja. Biochem Soc Trans. 2008 Jun;36(Pt 3):464-8. doi: 10.1042/BST0360464. Biochem Soc Trans. 2008. PMID: 18481982 Review.

8

SOCS3 tyrosine phosphorylation as a potential bio-marker for myeloproliferative neoplasms associated with mutant JAK2 kinases.

Elliott J, Suessmuth Y, Scott LM, Nahlik K, McMullin MF, Constantinescu SN, Green AR, Johnston JA. Elliott J, et al. Among authors: johnston ja. Haematologica. 2009 Apr;94(4):576-80. doi: 10.3324/haematol.2008.002352. Epub 2009 Feb 19. Haematologica. 2009. PMID: 19229050 Free PMC article.

9

A new polycythaemia vera-associated SOCS3 SH2 mutant (SOCS3F136L) cannot regulate erythropoietin responses.

Suessmuth Y, Elliott J, Percy MJ, Inami M, Attal H, Harrison CN, Inokuchi K, McMullin MF, Johnston JA. Suessmuth Y, et al. Among authors: johnston ja. Br J Haematol. 2009 Nov;147(4):450-8. doi: 10.1111/j.1365-2141.2009.07860.x. Epub 2009 Sep 5. Br J Haematol. 2009. PMID: 19735488 Free PMC article.

10

Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production.

Boyd CR, Orr SJ, Spence S, Burrows JF, Elliott J, Carroll HP, Brennan K, Ní Gabhann J, Coulter WA, Jones C, Crocker PR, Johnston JA, Jefferies CA. Boyd CR, et al. Among authors: johnston ja. J Immunol. 2009 Dec 15;183(12):7703-9. doi: 10.4049/jimmunol.0902780. J Immunol. 2009. PMID: 19933851 Free PMC article.

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