Sechaud R - Search Results

1

Phase II clinical evaluation of deferasirox, a once-daily oral chelating agent, in pediatric patients with beta-thalassemia major.

Galanello R, Piga A, Forni GL, Bertrand Y, Foschini ML, Bordone E, Leoni G, Lavagetto A, Zappu A, Longo F, Maseruka H, Hewson N, Sechaud R, Belleli R, Alberti D. Galanello R, et al. Among authors: sechaud r. Haematologica. 2006 Oct;91(10):1343-51. Haematologica. 2006. PMID: 17018383 Clinical Trial.

2

Safety, tolerability, and pharmacokinetics of ICL670, a new orally active iron-chelating agent in patients with transfusion-dependent iron overload due to beta-thalassemia.

Galanello R, Piga A, Alberti D, Rouan MC, Bigler H, Séchaud R. Galanello R, et al. Among authors: sechaud r. J Clin Pharmacol. 2003 Jun;43(6):565-72. J Clin Pharmacol. 2003. PMID: 12817519 Clinical Trial.

3

Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload.

Piga A, Galanello R, Forni GL, Cappellini MD, Origa R, Zappu A, Donato G, Bordone E, Lavagetto A, Zanaboni L, Sechaud R, Hewson N, Ford JM, Opitz H, Alberti D. Piga A, et al. Among authors: sechaud r. Haematologica. 2006 Jul;91(7):873-80. Haematologica. 2006. PMID: 16818273 Clinical Trial.

4

Effect of food, type of food, and time of food intake on deferasirox bioavailability: recommendations for an optimal deferasirox administration regimen.

Galanello R, Piga A, Cappellini MD, Forni GL, Zappu A, Origa R, Dutreix C, Belleli R, Ford JM, Rivière GJ, Balez S, Alberti D, Séchaud R. Galanello R, et al. Among authors: sechaud r. J Clin Pharmacol. 2008 Apr;48(4):428-35. doi: 10.1177/0091270007313327. Epub 2008 Feb 15. J Clin Pharmacol. 2008. PMID: 18281442 Clinical Trial.

5

Absolute oral bioavailability and disposition of deferasirox in healthy human subjects.

Séchaud R, Robeva A, Belleli R, Balez S. Séchaud R, et al. J Clin Pharmacol. 2008 Aug;48(8):919-25. doi: 10.1177/0091270008320316. Epub 2008 May 28. J Clin Pharmacol. 2008. PMID: 18508948 Clinical Trial.

6

Absence of an effect of a single-dose deferasirox on the steady-state pharmacokinetics of digoxin.

Sechaud R, Robeva A, Belleli R, Balez S. Sechaud R, et al. Int J Clin Pharmacol Ther. 2008 Oct;46(10):519-26. doi: 10.5414/cpp46519. Int J Clin Pharmacol Ther. 2008. PMID: 18826866 Clinical Trial.

7

Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial.

Nisbet-Brown E, Olivieri NF, Giardina PJ, Grady RW, Neufeld EJ, Séchaud R, Krebs-Brown AJ, Anderson JR, Alberti D, Sizer KC, Nathan DG. Nisbet-Brown E, et al. Among authors: sechaud r. Lancet. 2003 May 10;361(9369):1597-602. doi: 10.1016/S0140-6736(03)13309-0. Lancet. 2003. PMID: 12747879 Clinical Trial.

8

Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state.

Waldmeier F, Bruin GJ, Glaenzel U, Hazell K, Sechaud R, Warrington S, Porter JB. Waldmeier F, et al. Among authors: sechaud r. Drug Metab Dispos. 2010 May;38(5):808-16. doi: 10.1124/dmd.109.030833. Epub 2010 Jan 22. Drug Metab Dispos. 2010. PMID: 20097723 Clinical Trial.

9

Relative bioavailability of deferasirox tablets administered without dispersion and dispersed in various drinks.

Séchaud R, Dutreix C, Balez S, Pommier F, Dumortier T, Morisson S, Brun E. Séchaud R, et al. Int J Clin Pharmacol Ther. 2008 Feb;46(2):102-8. doi: 10.5414/cpp46102. Int J Clin Pharmacol Ther. 2008. PMID: 18218291 Clinical Trial.

10

Deferasirox does not induce QT/QTc-prolongation in healthy subjects.

Sechaud R, Dumortier T, Balez S. Sechaud R, et al. Int J Clin Pharmacol Ther. 2009 May;47(5):321-7. doi: 10.5414/cpp47321. Int J Clin Pharmacol Ther. 2009. PMID: 19473594 Clinical Trial.

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