Cozar-Castellano I - Search Results

1

Cellular mechanism through which parathyroid hormone-related protein induces proliferation in arterial smooth muscle cells: definition of an arterial smooth muscle PTHrP/p27kip1 pathway.

Fiaschi-Taesch N, Sicari BM, Ubriani K, Bigatel T, Takane KK, Cozar-Castellano I, Bisello A, Law B, Stewart AF. Fiaschi-Taesch N, et al. Circ Res. 2006 Oct 27;99(9):933-42. doi: 10.1161/01.RES.0000248184.21644.20. Epub 2006 Oct 5. Circ Res. 2006. PMID: 17023675

2

Lessons from the first comprehensive molecular characterization of cell cycle control in rodent insulinoma cell lines.

Cozar-Castellano I, Harb G, Selk K, Takane K, Vasavada R, Sicari B, Law B, Zhang P, Scott DK, Fiaschi-Taesch N, Stewart AF. Cozar-Castellano I, et al. Diabetes. 2008 Nov;57(11):3056-68. doi: 10.2337/db08-0393. Epub 2008 Jul 23. Diabetes. 2008. PMID: 18650366 Free PMC article.

3

Mutant parathyroid hormone-related protein, devoid of the nuclear localization signal, markedly inhibits arterial smooth muscle cell cycle and neointima formation by coordinate up-regulation of p15Ink4b and p27kip1.

Fiaschi-Taesch N, Sicari B, Ubriani K, Cozar-Castellano I, Takane KK, Stewart AF. Fiaschi-Taesch N, et al. Endocrinology. 2009 Mar;150(3):1429-39. doi: 10.1210/en.2008-0737. Epub 2008 Oct 9. Endocrinology. 2009. PMID: 18845646

4

Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo.

Fiaschi-Taesch N, Bigatel TA, Sicari B, Takane KK, Salim F, Velazquez-Garcia S, Harb G, Selk K, Cozar-Castellano I, Stewart AF. Fiaschi-Taesch N, et al. Diabetes. 2009 Apr;58(4):882-93. doi: 10.2337/db08-0631. Epub 2009 Jan 9. Diabetes. 2009. PMID: 19136653 Free PMC article.

5

Induction of beta-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D1.

Cozar-Castellano I, Takane KK, Bottino R, Balamurugan AN, Stewart AF. Cozar-Castellano I, et al. Diabetes. 2004 Jan;53(1):149-59. doi: 10.2337/diabetes.53.1.149. Diabetes. 2004. PMID: 14693709

6

Molecular engineering human hepatocytes into pancreatic beta cells for diabetes therapy.

Cozar-Castellano I, Stewart AF. Cozar-Castellano I, et al. Proc Natl Acad Sci U S A. 2005 May 31;102(22):7781-2. doi: 10.1073/pnas.0503261102. Epub 2005 May 23. Proc Natl Acad Sci U S A. 2005. PMID: 15911749 Free PMC article. No abstract available.

7

Evaluation of beta-cell replication in mice transgenic for hepatocyte growth factor and placental lactogen: comprehensive characterization of the G1/S regulatory proteins reveals unique involvement of p21cip.

Cozar-Castellano I, Weinstock M, Haught M, Velázquez-Garcia S, Sipula D, Stewart AF. Cozar-Castellano I, et al. Diabetes. 2006 Jan;55(1):70-7. Diabetes. 2006. PMID: 16380478

8

Molecular control of cell cycle progression in the pancreatic beta-cell.

Cozar-Castellano I, Fiaschi-Taesch N, Bigatel TA, Takane KK, Garcia-Ocaña A, Vasavada R, Stewart AF. Cozar-Castellano I, et al. Endocr Rev. 2006 Jun;27(4):356-70. doi: 10.1210/er.2006-0004. Epub 2006 Apr 25. Endocr Rev. 2006. PMID: 16638909 Review.

9

The cell cycle inhibitory protein p21cip is not essential for maintaining beta-cell cycle arrest or beta-cell function in vivo.

Cozar-Castellano I, Haught M, Stewart AF. Cozar-Castellano I, et al. Diabetes. 2006 Dec;55(12):3271-8. doi: 10.2337/db06-0627. Diabetes. 2006. PMID: 17130470

10

Tissue-specific deletion of the retinoblastoma protein in the pancreatic beta-cell has limited effects on beta-cell replication, mass, and function.

Vasavada RC, Cozar-Castellano I, Sipula D, Stewart AF. Vasavada RC, et al. Diabetes. 2007 Jan;56(1):57-64. doi: 10.2337/db06-0517. Diabetes. 2007. PMID: 17192465

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