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Preparation of novel anthranilic acids as antibacterial agents: extensive evaluation of structural and physical properties on antibacterial activity and human serum albumin affinity.
Thorarensen A, Li J, Wakefield BD, Romero DL, Marotti KR, Sweeney MT, Zurenko GE, Sarver RW. Thorarensen A, et al. Among authors: sweeney mt. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3113-6. doi: 10.1016/j.bmcl.2007.03.036. Epub 2007 Mar 15. Bioorg Med Chem Lett. 2007. PMID: 17400450
Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors.
Miller AA, Bundy GL, Mott JE, Skepner JE, Boyle TP, Harris DW, Hromockyj AE, Marotti KR, Zurenko GE, Munzner JB, Sweeney MT, Bammert GF, Hamel JC, Ford CW, Zhong WZ, Graber DR, Martin GE, Han F, Dolak LA, Seest EP, Ruble JC, Kamilar GM, Palmer JR, Banitt LS, Hurd AR, Barbachyn MR. Miller AA, et al. Among authors: sweeney mt. Antimicrob Agents Chemother. 2008 Aug;52(8):2806-12. doi: 10.1128/AAC.00247-08. Epub 2008 Jun 2. Antimicrob Agents Chemother. 2008. PMID: 18519725 Free PMC article.
Bacterial translation inhibitors, 1-acylindazol-3-ols as anthranilic acid mimics.
Stiff C, Graber DR, Thorarensen A, Wakefield BD, Marotti KR, Melchior EP, Sweeney MT, Han F, Rohrer DC, Zurenko GE, Romero DL. Stiff C, et al. Among authors: sweeney mt. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6293-7. doi: 10.1016/j.bmcl.2007.08.041. Epub 2007 Aug 25. Bioorg Med Chem Lett. 2008. PMID: 18951783
Enols as potent antibacterial agents.
Thorarensen A, Zurenko GE, Sweeney MT, Marotti KR, Boyle TP. Thorarensen A, et al. Among authors: sweeney mt. Bioorg Med Chem Lett. 2001 Nov 19;11(22):2931-4. doi: 10.1016/s0960-894x(01)00587-x. Bioorg Med Chem Lett. 2001. PMID: 11677129
41 results