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Discovering new classes of Brugia malayi asparaginyl-tRNA synthetase inhibitors and relating specificity to conformational change.
Sukuru SC, Crepin T, Milev Y, Marsh LC, Hill JB, Anderson RJ, Morris JC, Rohatgi A, O'Mahony G, Grøtli M, Danel F, Page MG, Härtlein M, Cusack S, Kron MA, Kuhn LA. Sukuru SC, et al. Among authors: crepin t. J Comput Aided Mol Des. 2006 Mar;20(3):159-78. doi: 10.1007/s10822-006-9043-5. Epub 2006 Apr 28. J Comput Aided Mol Des. 2006. PMID: 16645791
[Trap the product to specifically inhibit the enzyme].
Crépin T, Cusack S. Crépin T, et al. Med Sci (Paris). 2007 Dec;23(12):1087-9. doi: 10.1051/medsci/200723121087. Med Sci (Paris). 2007. PMID: 18154708 Free article. French. No abstract available.
The structural basis for cap binding by influenza virus polymerase subunit PB2.
Guilligay D, Tarendeau F, Resa-Infante P, Coloma R, Crepin T, Sehr P, Lewis J, Ruigrok RW, Ortin J, Hart DJ, Cusack S. Guilligay D, et al. Among authors: crepin t. Nat Struct Mol Biol. 2008 May;15(5):500-6. doi: 10.1038/nsmb.1421. Epub 2008 May 4. Nat Struct Mol Biol. 2008. PMID: 18454157
[New strategy for targeting influenza virus replication].
Dias A, Bouvier D, Cusack S, Ruigrok RW, Crépin T. Dias A, et al. Among authors: crepin t. Med Sci (Paris). 2009 Apr;25(4):352-4. doi: 10.1051/medsci/2009254352. Med Sci (Paris). 2009. PMID: 19409186 Free article. French. No abstract available.
99 results