Hu Z - Search Results

1

Precursor-directed biosynthesis of 6-deoxyerythronolide B analogues is improved by removal of the initial catalytic sites of the polyketide synthase.

Ward SL, Desai RP, Hu Z, Gramajo H, Katz L. Ward SL, et al. Among authors: hu z. J Ind Microbiol Biotechnol. 2007 Jan;34(1):9-15. doi: 10.1007/s10295-006-0156-6. Epub 2006 Oct 11. J Ind Microbiol Biotechnol. 2007. PMID: 17033784

2

Approaches to stabilization of inter-domain recombination in polyketide synthase gene expression plasmids.

Hu Z, Desai RP, Volchegursky Y, Leaf T, Woo E, Licari P, Santi DV, Hutchinson CR, McDaniel R. Hu Z, et al. J Ind Microbiol Biotechnol. 2003 Mar;30(3):161-7. doi: 10.1007/s10295-003-0029-1. Epub 2003 Mar 1. J Ind Microbiol Biotechnol. 2003. PMID: 12715253

3

Combining classical, genetic, and process strategies for improved precursor-directed production of 6-deoxyerythronolide B analogues.

Desai RP, Leaf T, Hu Z, Hutchinson CR, Hong A, Byng G, Galazzo J, Licari P. Desai RP, et al. Among authors: hu z. Biotechnol Prog. 2004 Jan-Feb;20(1):38-43. doi: 10.1021/bp034171u. Biotechnol Prog. 2004. PMID: 14763821

4

Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.

Ward SL, Hu Z, Schirmer A, Reid R, Revill WP, Reeves CD, Petrakovsky OV, Dong SD, Katz L. Ward SL, et al. Among authors: hu z. Antimicrob Agents Chemother. 2004 Dec;48(12):4703-12. doi: 10.1128/AAC.48.12.4703-4712.2004. Antimicrob Agents Chemother. 2004. PMID: 15561847 Free PMC article.

5

Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea.

Volchegursky Y, Hu Z, Katz L, McDaniel R. Volchegursky Y, et al. Among authors: hu z. Mol Microbiol. 2000 Aug;37(4):752-62. doi: 10.1046/j.1365-2958.2000.02059.x. Mol Microbiol. 2000. PMID: 10972798 Free article.

6

The leptomycin gene cluster and its heterologous expression in Streptomyces lividans.

Hu Z, Reid R, Gramajo H. Hu Z, et al. J Antibiot (Tokyo). 2005 Oct;58(10):625-33. doi: 10.1038/ja.2005.86. J Antibiot (Tokyo). 2005. PMID: 16392678

7

Chemobiosynthesis of novel 6-deoxyerythronolide B analogues by mutation of the loading module of 6-deoxyerythronolide B synthase 1.

Murli S, MacMillan KS, Hu Z, Ashley GW, Dong SD, Kealey JT, Reeves CD, Kennedy J. Murli S, et al. Among authors: hu z. Appl Environ Microbiol. 2005 Aug;71(8):4503-9. doi: 10.1128/AEM.71.8.4503-4509.2005. Appl Environ Microbiol. 2005. PMID: 16085842 Free PMC article.

8

Rapid engineering of polyketide overproduction by gene transfer to industrially optimized strains.

Rodriguez E, Hu Z, Ou S, Volchegursky Y, Hutchinson CR, McDaniel R. Rodriguez E, et al. Among authors: hu z. J Ind Microbiol Biotechnol. 2003 Aug;30(8):480-8. doi: 10.1007/s10295-003-0045-1. Epub 2003 Apr 16. J Ind Microbiol Biotechnol. 2003. PMID: 12698320

9

Enhanced heterologous polyketide production in Streptomyces by exploiting plasmid co-integration.

Hu Z, Hopwood DA, Hutchinson CR. Hu Z, et al. J Ind Microbiol Biotechnol. 2003 Aug;30(8):516-22. doi: 10.1007/s10295-003-0064-y. Epub 2003 Jun 21. J Ind Microbiol Biotechnol. 2003. PMID: 12827516

10

A specific role of the Saccharopolyspora erythraea thioesterase II gene in the function of modular polyketide synthases.

Hu Z, Pfeifer BA, Chao E, Murli S, Kealey J, Carney JR, Ashley G, Khosla C, Hutchinson CR. Hu Z, et al. Microbiology (Reading). 2003 Aug;149(Pt 8):2213-2225. doi: 10.1099/mic.0.26015-0. Microbiology (Reading). 2003. PMID: 12904561 Free article.

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