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Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
Lorenzi PL, Reinhold WC, Rudelius M, Gunsior M, Shankavaram U, Bussey KJ, Scherf U, Eichler GS, Martin SE, Chin K, Gray JW, Kohn EC, Horak ID, Von Hoff DD, Raffeld M, Goldsmith PK, Caplen NJ, Weinstein JN. Lorenzi PL, et al. Among authors: horak id. Mol Cancer Ther. 2006 Nov;5(11):2613-23. doi: 10.1158/1535-7163.MCT-06-0447. Epub 2006 Nov 6. Mol Cancer Ther. 2006. PMID: 17088436
Reduced expression of the androgen receptor by third generation of antisense shows antitumor activity in models of prostate cancer.
Zhang Y, Castaneda S, Dumble M, Wang M, Mileski M, Qu Z, Kim S, Shi V, Kraft P, Gao Y, Pak J, Sapra P, Bandaru R, Zhao H, Vessella RL, Horak ID, Greenberger LM. Zhang Y, et al. Among authors: horak id. Mol Cancer Ther. 2011 Dec;10(12):2309-19. doi: 10.1158/1535-7163.MCT-11-0329. Epub 2011 Oct 25. Mol Cancer Ther. 2011. PMID: 22027692
Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab.
Iida M, Bahrar H, Brand TM, Pearson HE, Coan JP, Orbuch RA, Flanigan BG, Swick AD, Prabakaran PJ, Lantto J, Horak ID, Kragh M, Salgia R, Kimple RJ, Wheeler DL. Iida M, et al. Among authors: horak id. Mol Cancer Ther. 2016 Sep;15(9):2175-86. doi: 10.1158/1535-7163.MCT-16-0012. Epub 2016 Jul 15. Mol Cancer Ther. 2016. PMID: 27422810 Free PMC article.
Simultaneous Targeting of Two Distinct Epitopes on MET Effectively Inhibits MET- and HGF-Driven Tumor Growth by Multiple Mechanisms.
Grandal MM, Havrylov S, Poulsen TT, Koefoed K, Dahlman A, Galler GR, Conrotto P, Collins S, Eriksen KW, Kaufman D, Woude GFV, Jacobsen HJ, Horak ID, Kragh M, Lantto J, Bouquin T, Park M, Pedersen MW. Grandal MM, et al. Among authors: horak id. Mol Cancer Ther. 2017 Dec;16(12):2780-2791. doi: 10.1158/1535-7163.MCT-17-0374. Epub 2017 Aug 11. Mol Cancer Ther. 2017. PMID: 28802255
Development of humanized antibodies as cancer therapeutics.
Qu Z, Griffiths GL, Wegener WA, Chang CH, Govindan SV, Horak ID, Hansen HJ, Goldenberg DM. Qu Z, et al. Among authors: horak id. Methods. 2005 May;36(1):84-95. doi: 10.1016/j.ymeth.2005.01.008. Methods. 2005. PMID: 15848077
87 results