Rothman RB - Search Results

1

An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization.

Groer CE, Tidgewell K, Moyer RA, Harding WW, Rothman RB, Prisinzano TE, Bohn LM. Groer CE, et al. Among authors: rothman rb. Mol Pharmacol. 2007 Feb;71(2):549-57. doi: 10.1124/mol.106.028258. Epub 2006 Nov 7. Mol Pharmacol. 2007. PMID: 17090705 Free PMC article.

2

Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands.

Harding WW, Tidgewell K, Byrd N, Cobb H, Dersch CM, Butelman ER, Rothman RB, Prisinzano TE. Harding WW, et al. Among authors: rothman rb. J Med Chem. 2005 Jul 28;48(15):4765-71. doi: 10.1021/jm048963m. J Med Chem. 2005. PMID: 16033256

3

Synthetic studies of neoclerodane diterpenes from Salvia divinorum: semisynthesis of salvinicins A and B and other chemical transformations of salvinorin A.

Harding WW, Schmidt M, Tidgewell K, Kannan P, Holden KG, Gilmour B, Navarro H, Rothman RB, Prisinzano TE. Harding WW, et al. Among authors: rothman rb. J Nat Prod. 2006 Jan;69(1):107-12. doi: 10.1021/np050398i. J Nat Prod. 2006. PMID: 16441078 Free PMC article.

4

Synthesis of salvinorin A analogues as opioid receptor probes.

Tidgewell K, Harding WW, Lozama A, Cobb H, Shah K, Kannan P, Dersch CM, Parrish D, Deschamps JR, Rothman RB, Prisinzano TE. Tidgewell K, et al. Among authors: rothman rb. J Nat Prod. 2006 Jun;69(6):914-8. doi: 10.1021/np060094b. J Nat Prod. 2006. PMID: 16792410 Free article.

5

Salvinorin A: allosteric interactions at the mu-opioid receptor.

Rothman RB, Murphy DL, Xu H, Godin JA, Dersch CM, Partilla JS, Tidgewell K, Schmidt M, Prisinzano TE. Rothman RB, et al. J Pharmacol Exp Ther. 2007 Feb;320(2):801-10. doi: 10.1124/jpet.106.113167. Epub 2006 Oct 23. J Pharmacol Exp Ther. 2007. PMID: 17060492

6

A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence.

Xu H, Partilla JS, Wang X, Rutherford JM, Tidgewell K, Prisinzano TE, Bohn LM, Rothman RB. Xu H, et al. Among authors: rothman rb. Synapse. 2007 Mar;61(3):166-75. doi: 10.1002/syn.20356. Synapse. 2007. PMID: 17152090

7

Herkinorin analogues with differential beta-arrestin-2 interactions.

Tidgewell K, Groer CE, Harding WW, Lozama A, Schmidt M, Marquam A, Hiemstra J, Partilla JS, Dersch CM, Rothman RB, Bohn LM, Prisinzano TE. Tidgewell K, et al. Among authors: rothman rb. J Med Chem. 2008 Apr 24;51(8):2421-31. doi: 10.1021/jm701162g. Epub 2008 Apr 2. J Med Chem. 2008. PMID: 18380425 Free PMC article.

8

Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring.

Harding WW, Schmidt M, Tidgewell K, Kannan P, Holden KG, Dersch CM, Rothman RB, Prisinzano TE. Harding WW, et al. Among authors: rothman rb. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3170-4. doi: 10.1016/j.bmcl.2006.03.062. Epub 2006 Apr 18. Bioorg Med Chem Lett. 2006. PMID: 16621556

9

Synthetic studies of neoclerodane diterpenes from Salvia divinorum: preparation and opioid receptor activity of salvinicin analogues.

Simpson DS, Katavic PL, Lozama A, Harding WW, Parrish D, Deschamps JR, Dersch CM, Partilla JS, Rothman RB, Navarro H, Prisinzano TE. Simpson DS, et al. Among authors: rothman rb. J Med Chem. 2007 Jul 26;50(15):3596-603. doi: 10.1021/jm070393d. Epub 2007 Jun 20. J Med Chem. 2007. PMID: 17580847

10

Synthetic studies of neoclerodane diterpenes from Salvia divinorum: exploration of the 1-position.

Holden KG, Tidgewell K, Marquam A, Rothman RB, Navarro H, Prisinzano TE. Holden KG, et al. Among authors: rothman rb. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6111-5. doi: 10.1016/j.bmcl.2007.09.050. Epub 2007 Sep 15. Bioorg Med Chem Lett. 2007. PMID: 17904842 Free PMC article.

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