Pemberton N - Search Results

1

Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria.

Pinkner JS, Remaut H, Buelens F, Miller E, Aberg V, Pemberton N, Hedenström M, Larsson A, Seed P, Waksman G, Hultgren SJ, Almqvist F. Pinkner JS, et al. Among authors: pemberton n. Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17897-902. doi: 10.1073/pnas.0606795103. Epub 2006 Nov 10. Proc Natl Acad Sci U S A. 2006. PMID: 17098869 Free PMC article.

2

NMR studies of interactions between periplasmic chaperones from uropathogenic E. coli and pilicides that interfere with chaperone function and pilus assembly.

Hedenström M, Emtenäs H, Pemberton N, Aberg V, Hultgren SJ, Pinkner JS, Tegman V, Almqvist F, Sethson I, Kihlberg J. Hedenström M, et al. Among authors: pemberton n. Org Biomol Chem. 2005 Dec 7;3(23):4193-200. doi: 10.1039/b511857c. Epub 2005 Oct 31. Org Biomol Chem. 2005. PMID: 16294247

3

Microwave-assisted synthesis of highly substituted aminomethylated 2-pyridones.

Pemberton N, Aberg V, Almstedt H, Westermark A, Almqvist F. Pemberton N, et al. J Org Chem. 2004 Nov 12;69(23):7830-5. doi: 10.1021/jo048554y. J Org Chem. 2004. PMID: 15527258

4

Synthesis of multi ring-fused 2-pyridones via an acyl-ketene imine cyclocondensation.

Pemberton N, Jakobsson L, Almqvist F. Pemberton N, et al. Org Lett. 2006 Mar 2;8(5):935-8. doi: 10.1021/ol052998e. Org Lett. 2006. PMID: 16494478

5

Cycloaddition of delta2-thiazolines and acyl ketenes under acidic conditions results in bicyclic 1,3-oxazinones and not 6-acylpenams as earlier reported.

Pemberton N, Emtenäs H, Boström D, Domaille PJ, Greenberg WA, Levin MD, Zhu Z, Almqvist F. Pemberton N, et al. Org Lett. 2005 Mar 17;7(6):1019-21. doi: 10.1021/ol047528j. Org Lett. 2005. PMID: 15760128

6

Synthesis of 2-alkyl-substituted chromone derivatives using microwave irradiation.

Fridén-Saxin M, Pemberton N, Andersson Kda S, Dyrager C, Friberg A, Grøtli M, Luthman K. Fridén-Saxin M, et al. Among authors: pemberton n. J Org Chem. 2009 Apr 3;74(7):2755-9. doi: 10.1021/jo802783z. J Org Chem. 2009. PMID: 19323574

7

KHMDS enhanced SmI(2)-mediated reformatsky type alpha-cyanation.

Ankner T, Fridén-Saxin M, Pemberton N, Seifert T, Grøtli M, Luthman K, Hilmersson G. Ankner T, et al. Among authors: pemberton n. Org Lett. 2010 May 21;12(10):2210-3. doi: 10.1021/ol100424y. Org Lett. 2010. PMID: 20429501

8

Synthesis and functionalization of cyclic sulfonimidamides: a novel chiral heterocyclic carboxylic Acid bioisostere.

Pemberton N, Graden H, Evertsson E, Bratt E, Lepistö M, Johannesson P, Svensson PH. Pemberton N, et al. ACS Med Chem Lett. 2012 May 30;3(7):574-8. doi: 10.1021/ml3000935. eCollection 2012 Jul 12. ACS Med Chem Lett. 2012. PMID: 24900513 Free PMC article.

9

Design and Synthesis of Soluble and Cell-Permeable PI3Kδ Inhibitors for Long-Acting Inhaled Administration.

Perry MWD, Björhall K, Bonn B, Carlsson J, Chen Y, Eriksson A, Fredlund L, Hao H, Holden NS, Karabelas K, Lindmark H, Liu F, Pemberton N, Petersen J, Rodrigo Blomqvist S, Smith RW, Svensson T, Terstiege I, Tyrchan C, Yang W, Zhao S, Öster L. Perry MWD, et al. Among authors: pemberton n. J Med Chem. 2017 Jun 22;60(12):5057-5071. doi: 10.1021/acs.jmedchem.7b00401. Epub 2017 Jun 7. J Med Chem. 2017. PMID: 28520415 Free article.

10

Chroman-4-one and chromone based somatostatin β-turn mimetics.

Fridén-Saxin M, Seifert T, Malo M, da Silva Andersson K, Pemberton N, Dyrager C, Friberg A, Dahlén K, Wallén EA, Grøtli M, Luthman K. Fridén-Saxin M, et al. Among authors: pemberton n. Eur J Med Chem. 2016 May 23;114:59-64. doi: 10.1016/j.ejmech.2016.02.046. Epub 2016 Feb 21. Eur J Med Chem. 2016. PMID: 26974375

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