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Halofuginone inhibits NF-kappaB and p38 MAPK in activated T cells.
Leiba M, Cahalon L, Shimoni A, Lider O, Zanin-Zhorov A, Hecht I, Sela U, Vlodavsky I, Nagler A. Leiba M, et al. J Leukoc Biol. 2006 Aug;80(2):399-406. doi: 10.1189/jlb.0705409. Epub 2006 Jun 12. J Leukoc Biol. 2006. PMID: 16769768
Prior treatment with the tyrosine kinase inhibitors dasatinib and nilotinib allows stem cell transplantation (SCT) in a less advanced disease phase and does not increase SCT Toxicity in patients with chronic myelogenous leukemia and philadelphia positive acute lymphoblastic leukemia.
Shimoni A, Leiba M, Schleuning M, Martineau G, Renaud M, Koren-Michowitz M, Ribakovski E, le Coutre P, Arnold R, Guilhot F, Nagler A. Shimoni A, et al. Among authors: leiba m. Leukemia. 2009 Jan;23(1):190-4. doi: 10.1038/leu.2008.160. Epub 2008 Jul 3. Leukemia. 2009. PMID: 18596746 No abstract available.
82 results