Colombini M - Search Results

1

Phosphorothioate oligonucleotides reduce mitochondrial outer membrane permeability to ADP.

Tan W, Lai JC, Miller P, Stein CA, Colombini M. Tan W, et al. Among authors: colombini m. Am J Physiol Cell Physiol. 2007 Apr;292(4):C1388-97. doi: 10.1152/ajpcell.00490.2006. Epub 2006 Nov 29. Am J Physiol Cell Physiol. 2007. PMID: 17135295 Free article.

2

Phosphorothioate oligonucleotides block the VDAC channel.

Tan W, Loke YH, Stein CA, Miller P, Colombini M. Tan W, et al. Among authors: colombini m. Biophys J. 2007 Aug 15;93(4):1184-91. doi: 10.1529/biophysj.107.105379. Epub 2007 May 4. Biophys J. 2007. PMID: 17483171 Free PMC article.

3

VDAC closure increases calcium ion flux.

Tan W, Colombini M. Tan W, et al. Among authors: colombini m. Biochim Biophys Acta. 2007 Oct;1768(10):2510-5. doi: 10.1016/j.bbamem.2007.06.002. Epub 2007 Jun 12. Biochim Biophys Acta. 2007. PMID: 17617374 Free PMC article.

4

On the role of VDAC in apoptosis: fact and fiction.

Rostovtseva TK, Tan W, Colombini M. Rostovtseva TK, et al. Among authors: colombini m. J Bioenerg Biomembr. 2005 Jun;37(3):129-42. doi: 10.1007/s10863-005-6566-8. J Bioenerg Biomembr. 2005. PMID: 16167170

5

A pharmacologic target of G3139 in melanoma cells may be the mitochondrial VDAC.

Lai JC, Tan W, Benimetskaya L, Miller P, Colombini M, Stein CA. Lai JC, et al. Among authors: colombini m. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7494-9. doi: 10.1073/pnas.0602217103. Epub 2006 Apr 28. Proc Natl Acad Sci U S A. 2006. PMID: 16648253 Free PMC article.

6

Specific VDAC inhibitors: phosphorothioate oligonucleotides.

Stein CA, Colombini M. Stein CA, et al. Among authors: colombini m. J Bioenerg Biomembr. 2008 Jun;40(3):157-62. doi: 10.1007/s10863-008-9139-9. J Bioenerg Biomembr. 2008. PMID: 18654842 Review.

7

Comparison of d-g3139 and its enantiomer L-g3139 in melanoma cells demonstrates minimal in vitro but dramatic in vivo chiral dependency.

Lai JC, Brown BD, Voskresenskiy AM, Vonhoff S, Klussman S, Tan W, Colombini M, Weeratna R, Miller P, Benimetskaya L, Stein CA. Lai JC, et al. Among authors: colombini m. Mol Ther. 2007 Feb;15(2):270-8. doi: 10.1038/sj.mt.6300037. Mol Ther. 2007. PMID: 17235304 Free article.

8

Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells.

Head SA, Shi W, Zhao L, Gorshkov K, Pasunooti K, Chen Y, Deng Z, Li RJ, Shim JS, Tan W, Hartung T, Zhang J, Zhao Y, Colombini M, Liu JO. Head SA, et al. Among authors: colombini m. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7276-85. doi: 10.1073/pnas.1512867112. Epub 2015 Dec 10. Proc Natl Acad Sci U S A. 2015. PMID: 26655341 Free PMC article.

9

Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels.

Siskind LJ, Feinstein L, Yu T, Davis JS, Jones D, Choi J, Zuckerman JE, Tan W, Hill RB, Hardwick JM, Colombini M. Siskind LJ, et al. Among authors: colombini m. J Biol Chem. 2008 Mar 14;283(11):6622-30. doi: 10.1074/jbc.M706115200. Epub 2008 Jan 2. J Biol Chem. 2008. PMID: 18171672 Free PMC article.

We reported previously that at physiologically relevant levels, ceramides form stable channels in mitochondrial outer membranes capable of passing the largest proteins known to exit mitochondria during apoptosis (Siskind, L. J., Kolesnick, R. N., and Colombini, M. ( …

We reported previously that at physiologically relevant levels, ceramides form stable channels in mitochondrial outer membranes capable of p …

10

Beta-NADH decreases the permeability of the mitochondrial outer membrane to ADP by a factor of 6.

Lee AC, Zizi M, Colombini M. Lee AC, et al. Among authors: colombini m. J Biol Chem. 1994 Dec 9;269(49):30974-80. J Biol Chem. 1994. PMID: 7983033 Free article.

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