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Ablation of neuronal ceramide synthase 1 in mice decreases ganglioside levels and expression of myelin-associated glycoprotein in oligodendrocytes.
Ginkel C, Hartmann D, vom Dorp K, Zlomuzica A, Farwanah H, Eckhardt M, Sandhoff R, Degen J, Rabionet M, Dere E, Dörmann P, Sandhoff K, Willecke K. Ginkel C, et al. Among authors: sandhoff k, sandhoff r. J Biol Chem. 2012 Dec 7;287(50):41888-902. doi: 10.1074/jbc.M112.413500. Epub 2012 Oct 16. J Biol Chem. 2012. PMID: 23074226 Free PMC article.
Physiological substrates for human lysosomal beta -hexosaminidase S.
Hepbildikler ST, Sandhoff R, Kolzer M, Proia RL, Sandhoff K. Hepbildikler ST, et al. Among authors: sandhoff k, sandhoff r. J Biol Chem. 2002 Jan 25;277(4):2562-72. doi: 10.1074/jbc.M105457200. Epub 2001 Nov 13. J Biol Chem. 2002. PMID: 11707436 Free article.
However, the striking accumulation of anionic oligosaccharides in double knockout mice totally deficient in hexosaminidase activity but not in mice expressing Hex S (Sango, K., McDonald, M. P., Crawley, J. N., Mack, M. L., Tifft, C.J., Skop, E., Starr, C. M., Hoffmann, A., …
However, the striking accumulation of anionic oligosaccharides in double knockout mice totally deficient in hexosaminidase activity but not …
Emerging concepts of ganglioside metabolism.
Sandhoff R, Sandhoff K. Sandhoff R, et al. Among authors: sandhoff k. FEBS Lett. 2018 Dec;592(23):3835-3864. doi: 10.1002/1873-3468.13114. Epub 2018 Jun 16. FEBS Lett. 2018. PMID: 29802621 Free article. Review.
Ganglioside Metabolism in Health and Disease.
Sandhoff R, Schulze H, Sandhoff K. Sandhoff R, et al. Among authors: sandhoff k. Prog Mol Biol Transl Sci. 2018;156:1-62. doi: 10.1016/bs.pmbts.2018.01.002. Epub 2018 Mar 28. Prog Mol Biol Transl Sci. 2018. PMID: 29747811 Review.
402 results