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A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.
Verhaegen M, Bauer JA, Martín de la Vega C, Wang G, Wolter KG, Brenner JC, Nikolovska-Coleska Z, Bengtson A, Nair R, Elder JT, Van Brocklin M, Carey TE, Bradford CR, Wang S, Soengas MS. Verhaegen M, et al. Among authors: elder jt. Cancer Res. 2006 Dec 1;66(23):11348-59. doi: 10.1158/0008-5472.CAN-06-1748. Cancer Res. 2006. PMID: 17145881
BRAF and NRAS mutations in melanoma and melanocytic nevi.
Poynter JN, Elder JT, Fullen DR, Nair RP, Soengas MS, Johnson TM, Redman B, Thomas NE, Gruber SB. Poynter JN, et al. Among authors: elder jt. Melanoma Res. 2006 Aug;16(4):267-73. doi: 10.1097/01.cmr.0000222600.73179.f3. Melanoma Res. 2006. PMID: 16845322
BRAF and NRAS mutations in spitzoid melanocytic lesions.
Fullen DR, Poynter JN, Lowe L, Su LD, Elder JT, Nair RP, Johnson TM, Gruber SB. Fullen DR, et al. Among authors: elder jt. Mod Pathol. 2006 Oct;19(10):1324-32. doi: 10.1038/modpathol.3800653. Epub 2006 Jun 23. Mod Pathol. 2006. PMID: 16799476 Free article.
Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene.
Nair RP, Stuart PE, Nistor I, Hiremagalore R, Chia NVC, Jenisch S, Weichenthal M, Abecasis GR, Lim HW, Christophers E, Voorhees JJ, Elder JT. Nair RP, et al. Among authors: elder jt. Am J Hum Genet. 2006 May;78(5):827-851. doi: 10.1086/503821. Epub 2006 Mar 31. Am J Hum Genet. 2006. PMID: 16642438 Free PMC article.
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
Nair RP, Duffin KC, Helms C, Ding J, Stuart PE, Goldgar D, Gudjonsson JE, Li Y, Tejasvi T, Feng BJ, Ruether A, Schreiber S, Weichenthal M, Gladman D, Rahman P, Schrodi SJ, Prahalad S, Guthery SL, Fischer J, Liao W, Kwok PY, Menter A, Lathrop GM, Wise CA, Begovich AB, Voorhees JJ, Elder JT, Krueger GG, Bowcock AM, Abecasis GR; Collaborative Association Study of Psoriasis. Nair RP, et al. Among authors: elder jt. Nat Genet. 2009 Feb;41(2):199-204. doi: 10.1038/ng.311. Epub 2009 Jan 25. Nat Genet. 2009. PMID: 19169254 Free PMC article.
268 results