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A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.
Verhaegen M, Bauer JA, Martín de la Vega C, Wang G, Wolter KG, Brenner JC, Nikolovska-Coleska Z, Bengtson A, Nair R, Elder JT, Van Brocklin M, Carey TE, Bradford CR, Wang S, Soengas MS. Verhaegen M, et al. Among authors: soengas ms. Cancer Res. 2006 Dec 1;66(23):11348-59. doi: 10.1158/0008-5472.CAN-06-1748. Cancer Res. 2006. PMID: 17145881
Anti-oxidant treatment enhances anti-tumor cytotoxicity of (-)-gossypol.
Sikora MJ, Bauer JA, Verhaegen M, Belbin TJ, Prystowsky MB, Taylor JC, Brenner JC, Wang S, Soengas MS, Bradford CR, Carey TE. Sikora MJ, et al. Among authors: soengas ms. Cancer Biol Ther. 2008 May;7(5):767-76. doi: 10.4161/cbt.7.5.5767. Epub 2008 May 20. Cancer Biol Ther. 2008. PMID: 18376141 Free PMC article.
Melanoma proliferation and chemoresistance controlled by the DEK oncogene.
Khodadoust MS, Verhaegen M, Kappes F, Riveiro-Falkenbach E, Cigudosa JC, Kim DS, Chinnaiyan AM, Markovitz DM, Soengas MS. Khodadoust MS, et al. Among authors: soengas ms. Cancer Res. 2009 Aug 15;69(16):6405-13. doi: 10.1158/0008-5472.CAN-09-1063. Cancer Res. 2009. PMID: 19679545 Free PMC article.
E2F1-dependent oncogenic addiction of melanoma cells to MDM2.
Verhaegen M, Checinska A, Riblett MB, Wang S, Soengas MS. Verhaegen M, et al. Among authors: soengas ms. Oncogene. 2012 Feb 16;31(7):828-41. doi: 10.1038/onc.2011.277. Epub 2011 Jul 11. Oncogene. 2012. PMID: 21743494 Free PMC article.
BRAF and NRAS mutations in melanoma and melanocytic nevi.
Poynter JN, Elder JT, Fullen DR, Nair RP, Soengas MS, Johnson TM, Redman B, Thomas NE, Gruber SB. Poynter JN, et al. Among authors: soengas ms. Melanoma Res. 2006 Aug;16(4):267-73. doi: 10.1097/01.cmr.0000222600.73179.f3. Melanoma Res. 2006. PMID: 16845322
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S, Deng X, Zhai D, Shi YX, Sneed T, Verhaegen M, Soengas M, Ruvolo VR, McQueen T, Schober WD, Watt JC, Jiffar T, Ling X, Marini FC, Harris D, Dietrich M, Estrov Z, McCubrey J, May WS, Reed JC, Andreeff M. Konopleva M, et al. Cancer Cell. 2006 Nov;10(5):375-88. doi: 10.1016/j.ccr.2006.10.006. Cancer Cell. 2006. PMID: 17097560 Free article.
84 results