Roberts JM - Search Results

1

p27(Kip1) and cyclin E expression and breast cancer survival after treatment with adjuvant chemotherapy.

Porter PL, Barlow WE, Yeh IT, Lin MG, Yuan XP, Donato E, Sledge GW, Shapiro CL, Ingle JN, Haskell CM, Albain KS, Roberts JM, Livingston RB, Hayes DF. Porter PL, et al. Among authors: roberts jm. J Natl Cancer Inst. 2006 Dec 6;98(23):1723-31. doi: 10.1093/jnci/djj467. J Natl Cancer Inst. 2006. PMID: 17148774 Free PMC article. Clinical Trial.

2

Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapy.

Zhao H, Faltermeier CM, Mendelsohn L, Porter PL, Clurman BE, Roberts JM. Zhao H, et al. Among authors: roberts jm. Oncotarget. 2014 Dec 30;5(24):12704-14. doi: 10.18632/oncotarget.2871. Oncotarget. 2014. PMID: 25587029 Free PMC article.

3

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients.

Porter PL, Malone KE, Heagerty PJ, Alexander GM, Gatti LA, Firpo EJ, Daling JR, Roberts JM. Porter PL, et al. Among authors: roberts jm. Nat Med. 1997 Feb;3(2):222-5. doi: 10.1038/nm0297-222. Nat Med. 1997. PMID: 9018243

4

Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer.

Timmerbeul I, Garrett-Engele CM, Kossatz U, Chen X, Firpo E, Grünwald V, Kamino K, Wilkens L, Lehmann U, Buer J, Geffers R, Kubicka S, Manns MP, Porter PL, Roberts JM, Malek NP. Timmerbeul I, et al. Among authors: roberts jm. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14009-14. doi: 10.1073/pnas.0606316103. Epub 2006 Sep 11. Proc Natl Acad Sci U S A. 2006. PMID: 16966613 Free PMC article.

5

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice.

Fero ML, Rivkin M, Tasch M, Porter P, Carow CE, Firpo E, Polyak K, Tsai LH, Broudy V, Perlmutter RM, Kaushansky K, Roberts JM. Fero ML, et al. Among authors: roberts jm. Cell. 1996 May 31;85(5):733-44. doi: 10.1016/s0092-8674(00)81239-8. Cell. 1996. PMID: 8646781 Free article.

6

MAD1 and p27(KIP1) cooperate to promote terminal differentiation of granulocytes and to inhibit Myc expression and cyclin E-CDK2 activity.

McArthur GA, Foley KP, Fero ML, Walkley CR, Deans AJ, Roberts JM, Eisenman RN. McArthur GA, et al. Among authors: roberts jm. Mol Cell Biol. 2002 May;22(9):3014-23. doi: 10.1128/MCB.22.9.3014-3023.2002. Mol Cell Biol. 2002. PMID: 11940659 Free PMC article.

7

A mouse model for cyclin E-dependent genetic instability and tumorigenesis.

Loeb KR, Kostner H, Firpo E, Norwood T, D Tsuchiya K, Clurman BE, Roberts JM. Loeb KR, et al. Among authors: roberts jm. Cancer Cell. 2005 Jul;8(1):35-47. doi: 10.1016/j.ccr.2005.06.010. Cancer Cell. 2005. PMID: 16023597 Free article.

8

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1).

Hiromura K, Pippin JW, Fero ML, Roberts JM, Shankland SJ. Hiromura K, et al. Among authors: roberts jm. J Clin Invest. 1999 Mar;103(5):597-604. doi: 10.1172/JCI5461. J Clin Invest. 1999. PMID: 10074476 Free PMC article.

9

A mechanism misregulating p27 in tumors discovered in a functional genomic screen.

Garrett-Engele CM, Tasch MA, Hwang HC, Fero ML, Perlmutter RM, Clurman BE, Roberts JM. Garrett-Engele CM, et al. Among authors: roberts jm. PLoS Genet. 2007 Dec;3(12):e219. doi: 10.1371/journal.pgen.0030219. PLoS Genet. 2007. PMID: 18069898 Free PMC article.

10

Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype.

Besson A, Hwang HC, Cicero S, Donovan SL, Gurian-West M, Johnson D, Clurman BE, Dyer MA, Roberts JM. Besson A, et al. Among authors: roberts jm. Genes Dev. 2007 Jul 15;21(14):1731-46. doi: 10.1101/gad.1556607. Epub 2007 Jul 12. Genes Dev. 2007. PMID: 17626791 Free PMC article.

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