Martínek V - Search Results

1

Modulation of CYP1A1-mediated oxidation of carcinogenic azo dye Sudan I and its binding to DNA by cytochrome b5.

Stiborová M, Martínek V, Schmeiser HH, Frei E. Stiborová M, et al. Among authors: martinek v. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:35-9. Neuro Endocrinol Lett. 2006. PMID: 17159775

2

Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.

Stiborová M, Martínek V, Rýdlová H, Hodek P, Frei E. Stiborová M, et al. Among authors: martinek v. Cancer Res. 2002 Oct 15;62(20):5678-84. Cancer Res. 2002. PMID: 12384524

3

Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers.

Stiborová M, Martínek V, Rýdlová H, Koblas T, Hodek P. Stiborová M, et al. Among authors: martinek v. Cancer Lett. 2005 Apr 8;220(2):145-54. doi: 10.1016/j.canlet.2004.07.036. Cancer Lett. 2005. PMID: 15766589

4

A one-electron oxidation of carcinogenic nonaminoazo dye Sudan I by horseradish peroxidase.

Semanska M, Dracinsky M, Martinek V, Hudecek J, Hodek P, Frei E, Stiborova M. Semanska M, et al. Among authors: martinek v. Neuro Endocrinol Lett. 2008 Oct;29(5):712-6. Neuro Endocrinol Lett. 2008. PMID: 18987613

5

Mechanism of formation of (deoxy)guanosine adducts derived from peroxidase-catalyzed oxidation of the carcinogenic nonaminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I).

Dracínský M, Cvacka J, Semanská M, Martínek V, Frei E, Stiborová M. Dracínský M, et al. Among authors: martinek v. Chem Res Toxicol. 2009 Nov;22(11):1765-73. doi: 10.1021/tx900201q. Chem Res Toxicol. 2009. PMID: 19813759

6

Preparation of apo-cytochrome b5 utilizing heme transfer to apo-myoglobin.

Mrazova B, Martinek V, Martinkova M, Sulc M, Frei E, Stiborova M. Mrazova B, et al. Among authors: martinek v. Neuro Endocrinol Lett. 2009;30 Suppl 1:72-9. Neuro Endocrinol Lett. 2009. PMID: 20027148

7

Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxy-naphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study.

Stiborová M, Martínek V, Semanská M, Hodek P, Dračínský M, Cvačka J, Schmeiser HH, Frei E. Stiborová M, et al. Among authors: martinek v. Interdiscip Toxicol. 2009 Sep;2(3):195-200. doi: 10.2478/v10102-009-0017-z. Epub 2009 Sep 28. Interdiscip Toxicol. 2009. PMID: 21217854 Free PMC article.

8

Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy.

Kotrbová V, Mrázová B, Moserová M, Martínek V, Hodek P, Hudeček J, Frei E, Stiborová M. Kotrbová V, et al. Among authors: martinek v. Biochem Pharmacol. 2011 Sep 15;82(6):669-80. doi: 10.1016/j.bcp.2011.06.003. Epub 2011 Jun 13. Biochem Pharmacol. 2011. PMID: 21683692

9

Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases.

Martinek V, Kubickova B, Arlt VM, Frei E, Schmeiser HH, Hudecek J, Stiborova M. Martinek V, et al. Neuro Endocrinol Lett. 2011;32 Suppl 1:57-70. Neuro Endocrinol Lett. 2011. PMID: 22167209

10

Cytochrome b5 increases cytochrome P450 3A4-mediated activation of anticancer drug ellipticine to 13-hydroxyellipticine whose covalent binding to DNA is elevated by sulfotransferases and N,O-acetyltransferases.

Stiborová M, Indra R, Moserová M, Cerná V, Rupertová M, Martínek V, Eckschlager T, Kizek R, Frei E. Stiborová M, et al. Among authors: martinek v. Chem Res Toxicol. 2012 May 21;25(5):1075-85. doi: 10.1021/tx3000335. Epub 2012 Mar 15. Chem Res Toxicol. 2012. PMID: 22390216

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