Grossman SJ - Search Results

1

Glucuronidation in the chimpanzee (Pan troglodytes): studies with acetaminophen, oestradiol and morphine.

Wong H, Grace JE Jr, Wright MR, Browning MR, Grossman SJ, Bai SA, Christ DD. Wong H, et al. Among authors: grossman sj. Xenobiotica. 2006 Dec;36(12):1178-90. doi: 10.1080/00498250600911028. Xenobiotica. 2006. PMID: 17162465

2

The chimpanzee (Pan troglodytes) as a pharmacokinetic model for selection of drug candidates: model characterization and application.

Wong H, Grossman SJ, Bai SA, Diamond S, Wright MR, Grace JE Jr, Qian M, He K, Yeleswaram K, Christ DD. Wong H, et al. Among authors: grossman sj. Drug Metab Dispos. 2004 Dec;32(12):1359-69. doi: 10.1124/dmd.104.000943. Epub 2004 Aug 27. Drug Metab Dispos. 2004. PMID: 15333515

3

N-in-1 dosing pharmacokinetics in drug discovery: experience, theoretical and practical considerations.

He K, Qian M, Wong H, Bai SA, He B, Brogdon B, Grace JE, Xin B, Wu J, Ren SX, Zeng H, Deng Y, Graden DM, Olah TV, Unger SE, Luettgen JM, Knabb RM, Pinto DJ, Lam PY, Duan J, Wexler RR, Decicco CP, Christ DD, Grossman SJ. He K, et al. Among authors: grossman sj. J Pharm Sci. 2008 Jul;97(7):2568-80. doi: 10.1002/jps.21196. J Pharm Sci. 2008. PMID: 17914718

4

Preclinical pharmacokinetics and pharmacodynamics of apixaban, a potent and selective factor Xa inhibitor.

He K, Luettgen JM, Zhang D, He B, Grace JE Jr, Xin B, Pinto DJ, Wong PC, Knabb RM, Lam PY, Wexler RR, Grossman SJ. He K, et al. Among authors: grossman sj. Eur J Drug Metab Pharmacokinet. 2011 Sep;36(3):129-39. doi: 10.1007/s13318-011-0037-x. Epub 2011 Apr 2. Eur J Drug Metab Pharmacokinet. 2011. PMID: 21461793

5

Increased hepatobiliary clearance of unconjugated thyroxine determines DMP 904-induced alterations in thyroid hormone homeostasis in rats.

Wong H, Lehman-McKeeman LD, Grubb MF, Grossman SJ, Bhaskaran VM, Solon EG, Shen HS, Gerson RJ, Car BD, Zhao B, Gemzik B. Wong H, et al. Among authors: grossman sj. Toxicol Sci. 2005 Apr;84(2):232-42. doi: 10.1093/toxsci/kfi094. Epub 2005 Jan 26. Toxicol Sci. 2005. PMID: 15673846

6

Synthesis and structure-activity relationships of 8-(pyrid-3-yl)pyrazolo[1,5-a]-1,3,5-triazines: potent, orally bioavailable corticotropin releasing factor receptor-1 (CRF1) antagonists.

Gilligan PJ, Clarke T, He L, Lelas S, Li YW, Heman K, Fitzgerald L, Miller K, Zhang G, Marshall A, Krause C, McElroy JF, Ward K, Zeller K, Wong H, Bai S, Saye J, Grossman S, Zaczek R, Arneric SP, Hartig P, Robertson D, Trainor G. Gilligan PJ, et al. J Med Chem. 2009 May 14;52(9):3084-92. doi: 10.1021/jm900025h. J Med Chem. 2009. PMID: 19361209

7

N-phenylphenylglycines as novel corticotropin releasing factor receptor antagonists.

Molteni V, Penzotti J, Wilson DM, Termin AP, Mao L, Crane CM, Hassman F, Wang T, Wong H, Miller KJ, Grossman S, Grootenhuis PD. Molteni V, et al. J Med Chem. 2004 May 6;47(10):2426-9. doi: 10.1021/jm049974i. J Med Chem. 2004. PMID: 15115386

8

In vitro and in vivo metabolism and pharmacokinetics of BMS-562086, a potent and orally bioavailable corticotropin-releasing factor-1 receptor antagonist.

Zhou L, Dockens RC, Liu-Kreyche P, Grossman SJ, Iyer RA. Zhou L, et al. Among authors: grossman sj. Drug Metab Dispos. 2012 Jun;40(6):1093-103. doi: 10.1124/dmd.111.043596. Epub 2012 Mar 1. Drug Metab Dispos. 2012. PMID: 22381334

9

Receptor occupancy of nonpeptide corticotropin-releasing factor 1 antagonist DMP696: correlation with drug exposure and anxiolytic efficacy.

Li YW, Hill G, Wong H, Kelly N, Ward K, Pierdomenico M, Ren S, Gilligan P, Grossman S, Trainor G, Taub R, McElroy J, Zazcek R. Li YW, et al. J Pharmacol Exp Ther. 2003 Apr;305(1):86-96. doi: 10.1124/jpet.102.045914. J Pharmacol Exp Ther. 2003. PMID: 12649356

10

8-(4-Methoxyphenyl)pyrazolo[1,5-a]-1,3,5-triazines: selective and centrally active corticotropin-releasing factor receptor-1 (CRF1) antagonists.

Gilligan PJ, He L, Clarke T, Tivitmahaisoon P, Lelas S, Li YW, Heman K, Fitzgerald L, Miller K, Zhang G, Marshall A, Krause C, McElroy J, Ward K, Shen H, Wong H, Grossman S, Nemeth G, Zaczek R, Arneric SP, Hartig P, Robertson DW, Trainor G. Gilligan PJ, et al. J Med Chem. 2009 May 14;52(9):3073-83. doi: 10.1021/jm9000242. J Med Chem. 2009. PMID: 19361210

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