Schlicker C - Search Results

1

The C2A-C2B linker defines the high affinity Ca(2+) binding mode of rabphilin-3A.

Montaville P, Schlicker C, Leonov A, Zweckstetter M, Sheldrick GM, Becker S. Montaville P, et al. Among authors: schlicker c. J Biol Chem. 2007 Feb 16;282(7):5015-5025. doi: 10.1074/jbc.M606746200. Epub 2006 Dec 13. J Biol Chem. 2007. PMID: 17166855 Free article.

2

Structural analysis of the PP2C phosphatase tPphA from Thermosynechococcus elongatus: a flexible flap subdomain controls access to the catalytic site.

Schlicker C, Fokina O, Kloft N, Grüne T, Becker S, Sheldrick GM, Forchhammer K. Schlicker C, et al. J Mol Biol. 2008 Feb 15;376(2):570-81. doi: 10.1016/j.jmb.2007.11.097. Epub 2007 Dec 5. J Mol Biol. 2008. PMID: 18164312

3

A third metal is required for catalytic activity of the signal-transducing protein phosphatase M tPphA.

Su J, Schlicker C, Forchhammer K. Su J, et al. Among authors: schlicker c. J Biol Chem. 2011 Apr 15;286(15):13481-8. doi: 10.1074/jbc.M109.036467. Epub 2011 Feb 10. J Biol Chem. 2011. PMID: 21310952 Free PMC article.

4

Structure-based development of novel adenylyl cyclase inhibitors.

Schlicker C, Rauch A, Hess KC, Kachholz B, Levin LR, Buck J, Steegborn C. Schlicker C, et al. J Med Chem. 2008 Aug 14;51(15):4456-64. doi: 10.1021/jm800481q. Epub 2008 Jul 17. J Med Chem. 2008. PMID: 18630896 Free PMC article.

5

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.

Schlicker C, Gertz M, Papatheodorou P, Kachholz B, Becker CF, Steegborn C. Schlicker C, et al. J Mol Biol. 2008 Oct 10;382(3):790-801. doi: 10.1016/j.jmb.2008.07.048. Epub 2008 Jul 25. J Mol Biol. 2008. PMID: 18680753

6

Structure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans.

Schlicker C, Hall RA, Vullo D, Middelhaufe S, Gertz M, Supuran CT, Mühlschlegel FA, Steegborn C. Schlicker C, et al. J Mol Biol. 2009 Jan 30;385(4):1207-20. doi: 10.1016/j.jmb.2008.11.037. Epub 2008 Nov 27. J Mol Biol. 2009. PMID: 19071134

7

Structure-based development of novel sirtuin inhibitors.

Schlicker C, Boanca G, Lakshminarasimhan M, Steegborn C. Schlicker C, et al. Aging (Albany NY). 2011 Sep;3(9):852-72. doi: 10.18632/aging.100388. Aging (Albany NY). 2011. PMID: 21937767 Free PMC article.

8

Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides.

Innocenti A, Hall RA, Schlicker C, Scozzafava A, Steegborn C, Mühlschlegel FA, Supuran CT. Innocenti A, et al. Among authors: schlicker c. Bioorg Med Chem. 2009 Jul 1;17(13):4503-9. doi: 10.1016/j.bmc.2009.05.002. Epub 2009 May 8. Bioorg Med Chem. 2009. PMID: 19450983

9

Crystal structure of the GAF-B domain from human phosphodiesterase 5.

Russwurm M, Schlicker C, Weyand M, Koesling D, Steegborn C. Russwurm M, et al. Among authors: schlicker c. Proteins. 2011 May;79(5):1682-7. doi: 10.1002/prot.22989. Epub 2011 Mar 21. Proteins. 2011. PMID: 21425347 No abstract available.

10

Crystal structure of mammalian selenocysteine-dependent iodothyronine deiodinase suggests a peroxiredoxin-like catalytic mechanism.

Schweizer U, Schlicker C, Braun D, Köhrle J, Steegborn C. Schweizer U, et al. Among authors: schlicker c. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10526-31. doi: 10.1073/pnas.1323873111. Epub 2014 Jul 7. Proc Natl Acad Sci U S A. 2014. PMID: 25002520 Free PMC article.

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