Almqvist F - Search Results

1

Intra-striatal infusion of the small molecule alpha-synuclein aggregator, FN075, does not enhance parkinsonism in a subclinical AAV-alpha-synuclein rat model.

Patton T, Comini G, Narasimhan K, Cairns AG, Ådén J, Almqvist F, Bemelmans A, Brouillet E, McKernan DP, Dowd E. Patton T, et al. Among authors: almqvist f. Eur J Neurosci. 2024 Sep;60(6):5234-5248. doi: 10.1111/ejn.16493. Epub 2024 Aug 14. Eur J Neurosci. 2024. PMID: 39143728

2

Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection.

Zou Z, Singh P, Pinkner JS, Obernuefemann CLP, Xu W, Nye TM, Dodson KW, Almqvist F, Hultgren SJ, Caparon MG. Zou Z, et al. Among authors: almqvist f. Sci Adv. 2024 Aug 2;10(31):eadn7979. doi: 10.1126/sciadv.adn7979. Epub 2024 Aug 2. Sci Adv. 2024. PMID: 39093975 Free PMC article.

3

Photoredox-Catalyzed Radical Coupling of C7-Chloromethyl-Substituted Thiazolino Ring-Fused 2-Pyridones with Quinoxalinones.

Hellgren V, Singh P, Kulkarni A, Bagheri N, Widengren J, Manavalan G, Almqvist F. Hellgren V, et al. Among authors: almqvist f. J Org Chem. 2024 Aug 16;89(16):11802-11810. doi: 10.1021/acs.joc.4c01224. Epub 2024 Jul 25. J Org Chem. 2024. PMID: 39051977 Free PMC article.

4

P-Factor(s) for Youth Psychopathology Across Informants and Models in 24 Societies.

Achenbach TM, Ivanova MY, Turner LV, Ritz H, Almqvist F, Bilenberg N, Bird H, Chahed M, Döpfner M, Erol N, Hannesdottir H, Kanbayashi Y, Lambert MC, Leung PWL, Liu J, Minaei A, Novik TS, Oh KJ, Petot D, Petot JM, Pomalima R, Raine A, Sawyer M, Simsek Z, Steinhausen HC, van der Ende J, Wolanczyk T, Zukauskiene R, Verhulst FC. Achenbach TM, et al. Among authors: almqvist f. J Clin Child Adolesc Psychol. 2024 May 28:1-10. doi: 10.1080/15374416.2024.2344159. Online ahead of print. J Clin Child Adolesc Psychol. 2024. PMID: 38805627

5

Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug-resistant Mycobacterium tuberculosis.

Harrison GA, Wang ER, Cho K, Mreyoud Y, Sarkar S, Almqvist F, Patti GJ, Stallings CL. Harrison GA, et al. Among authors: almqvist f. mBio. 2024 Mar 13;15(3):e0296823. doi: 10.1128/mbio.02968-23. Epub 2024 Jan 31. mBio. 2024. PMID: 38294237 Free PMC article.

6

Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection.

Zou Z, Obernuefemann CLP, Singh P, Pinkner JS, Xu W, Nye TM, Dodson KW, Almqvist F, Hultgren SJ, Caparon MG. Zou Z, et al. Among authors: almqvist f. bioRxiv [Preprint]. 2024 Jan 3:2024.01.02.573960. doi: 10.1101/2024.01.02.573960. bioRxiv. 2024. Update in: Sci Adv. 2024 Aug 2;10(31):eadn7979. doi: 10.1126/sciadv.adn7979 PMID: 38260261 Free PMC article. Updated. Preprint.

7

Synthesis of Three-Dimensional Ring Fused Heterocycles by a Selective [4 + 2] Cycloaddition Between Bicyclic Thiazolo 2-Pyridones and Arynes.

Sarkar S, Singh P, Edin S, Wendt OF, Almqvist F. Sarkar S, et al. Among authors: almqvist f. J Org Chem. 2024 Jan 5;89(1):731-739. doi: 10.1021/acs.joc.3c01957. Epub 2023 Dec 14. J Org Chem. 2024. PMID: 38093677 Free PMC article.

8

Design, Synthesis, and Evaluation of Novel Δ²-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant.

Sarkar S, Mayer Bridwell AE, Good JAD, Wang ER, McKee SR, Valenta J, Harrison GA, Flentie KN, Henry FL, Wixe T, Demirel P, Vagolu SK, Chatagnon J, Machelart A, Brodin P, Tønjum T, Stallings CL, Almqvist F. Sarkar S, et al. Among authors: almqvist f. J Med Chem. 2023 Aug 24;66(16):11056-11077. doi: 10.1021/acs.jmedchem.3c00358. Epub 2023 Jul 24. J Med Chem. 2023. PMID: 37485869 Free PMC article.

9

Structural insights into CodY activation and DNA recognition.

Hainzl T, Bonde M, Almqvist F, Johansson J, Sauer-Eriksson AE. Hainzl T, et al. Among authors: almqvist f. Nucleic Acids Res. 2023 Aug 11;51(14):7631-7648. doi: 10.1093/nar/gkad512. Nucleic Acids Res. 2023. PMID: 37326020 Free PMC article.

10

A Highly Substituted Ring-Fused 2-Pyridone Compound Targeting PrfA and the Efflux Regulator BrtA in Listeria monocytogenes.

Tükenmez H, Singh P, Sarkar S, Çakır M, Oliveira AH, Lindgren C, Vaitkevicius K, Bonde M, Sauer-Eriksson AE, Almqvist F, Johansson J. Tükenmez H, et al. Among authors: almqvist f. mBio. 2023 Jun 27;14(3):e0044923. doi: 10.1128/mbio.00449-23. Epub 2023 Apr 25. mBio. 2023. PMID: 37120759 Free PMC article.

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