Groll M - Search Results

1

TMC-95A analogues with endocyclic biphenyl ether group as proteasome inhibitors.

Kaiser M, Milbradt AG, Siciliano C, Assfalg-Machleidt I, Machleidt W, Groll M, Renner C, Moroder L. Kaiser M, et al. Among authors: groll m. Chem Biodivers. 2004 Jan;1(1):161-73. doi: 10.1002/cbdv.200490008. Chem Biodivers. 2004. PMID: 17191784

2

Synthesis, kinetic characterization and X-ray analysis of peptide aldehydes as inhibitors of the 20S proteasomes from Thermoplasma acidophilum and Saccharomyces cerevisiae.

Escherich A, Ditzel L, Musiol HJ, Groll M, Huber R, Moroder L. Escherich A, et al. Among authors: groll m. Biol Chem. 1997 Aug;378(8):893-8. doi: 10.1515/bchm.1997.378.8.893. Biol Chem. 1997. PMID: 9377486

3

Bifunctional inhibitors of the trypsin-like activity of eukaryotic proteasomes.

Loidl G, Groll M, Musiol HJ, Ditzel L, Huber R, Moroder L. Loidl G, et al. Among authors: groll m. Chem Biol. 1999 Apr;6(4):197-204. doi: 10.1016/S1074-5521(99)80036-2. Chem Biol. 1999. PMID: 10099130

4

Bivalency as a principle for proteasome inhibition.

Loidl G, Groll M, Musiol HJ, Huber R, Moroder L. Loidl G, et al. Among authors: groll m. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5418-22. doi: 10.1073/pnas.96.10.5418. Proc Natl Acad Sci U S A. 1999. PMID: 10318898 Free PMC article.

5

Synthesis of bivalent inhibitors of eucaryotic proteasomes.

Loidl G, Musiol HJ, Groll M, Huber R, Moroder L. Loidl G, et al. Among authors: groll m. J Pept Sci. 2000 Jan;6(1):36-46. doi: 10.1002/(SICI)1099-1387(200001)6:1<36::AID-PSC232>3.0.CO;2-2. J Pept Sci. 2000. PMID: 10674718

6

A gated channel into the proteasome core particle.

Groll M, Bajorek M, Köhler A, Moroder L, Rubin DM, Huber R, Glickman MH, Finley D. Groll M, et al. Nat Struct Biol. 2000 Nov;7(11):1062-7. doi: 10.1038/80992. Nat Struct Biol. 2000. PMID: 11062564

7

Crystal structure of the 20 S proteasome:TMC-95A complex: a non-covalent proteasome inhibitor.

Groll M, Koguchi Y, Huber R, Kohno J. Groll M, et al. J Mol Biol. 2001 Aug 17;311(3):543-8. doi: 10.1006/jmbi.2001.4869. J Mol Biol. 2001. PMID: 11493007

8

Probing structural determinants distal to the site of hydrolysis that control substrate specificity of the 20S proteasome.

Groll M, Nazif T, Huber R, Bogyo M. Groll M, et al. Chem Biol. 2002 May;9(5):655-62. doi: 10.1016/s1074-5521(02)00144-8. Chem Biol. 2002. PMID: 12031672

9

Navigation inside a protease: substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum.

Kim JS, Groll M, Musiol HJ, Behrendt R, Kaiser M, Moroder L, Huber R, Brandstetter H. Kim JS, et al. Among authors: groll m. J Mol Biol. 2002 Dec 13;324(5):1041-50. doi: 10.1016/s0022-2836(02)01153-1. J Mol Biol. 2002. PMID: 12470958

10

The core structure of TMC-95A is a promising lead for reversible proteasome inhibition.

Kaiser M, Groll M, Renner C, Huber R, Moroder L. Kaiser M, et al. Among authors: groll m. Angew Chem Int Ed Engl. 2002 Mar 1;41(5):780-3. doi: 10.1002/1521-3773(20020301)41:5<780::aid-anie780>3.0.co;2-v. Angew Chem Int Ed Engl. 2002. PMID: 12491334 No abstract available.

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