Stiborová M - Search Results

1

Oxidation pattern of the anticancer drug ellipticine by hepatic microsomes - similarity between human and rat systems.

Stiborová M, Borek-Dohalská L, Aimová D, Kotrbová V, Kukacková K, Janouchová K, Rupertová M, Ryslavá H, Hudecek J, Frei E. Stiborová M, et al. Gen Physiol Biophys. 2006 Sep;25(3):245-61. Gen Physiol Biophys. 2006. PMID: 17197724 Free article.

2

New selective inhibitors of cytochromes P450 2B and their application to antimutagenesis of tamoxifen.

Stiborová M, Borek-Dohalská L, Hodek P, Mráz J, Frei E. Stiborová M, et al. Arch Biochem Biophys. 2002 Jul 1;403(1):41-9. doi: 10.1016/S0003-9861(02)00259-X. Arch Biochem Biophys. 2002. PMID: 12061800

3

Rat microsomes activating the anticancer drug ellipticine to species covalently binding to deoxyguanosine in DNA are a suitable model mimicking ellipticine bioactivation in humans.

Stiborová M, Stiborová-Rupertová M, Borek-Dohalská L, Wiessler M, Frei E. Stiborová M, et al. Among authors: stiborova rupertova m. Chem Res Toxicol. 2003 Jan;16(1):38-47. doi: 10.1021/tx0200818. Chem Res Toxicol. 2003. PMID: 12693029

4

DNA adduct formation by the anticancer drug ellipticine in rats determined by 32P postlabeling.

Stiborová M, Breuer A, Aimová D, Stiborová-Rupertová M, Wiessler M, Frei E. Stiborová M, et al. Among authors: stiborova rupertova m. Int J Cancer. 2003 Dec 20;107(6):885-90. doi: 10.1002/ijc.11511. Int J Cancer. 2003. PMID: 14601046

5

The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide.

Stiborová M, Sejbal J, Borek-Dohalská L, Aimová D, Poljaková J, Forsterová K, Rupertová M, Wiesner J, Hudecek J, Wiessler M, Frei E. Stiborová M, et al. Cancer Res. 2004 Nov 15;64(22):8374-80. doi: 10.1158/0008-5472.CAN-04-2202. Cancer Res. 2004. PMID: 15548707

6

Antitumor drug ellipticine inhibits the activities of rat hepatic cytochromes P450.

Aimová D, Stiborová M. Aimová D, et al. Among authors: stiborova m. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005 Dec;149(2):437-40. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005. PMID: 16601806

7

Molecular mechanisms of antineoplastic action of an anticancer drug ellipticine.

Stiborova M, Rupertova M, Schmeiser HH, Frei E. Stiborova M, et al. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2006 Jul;150(1):13-23. doi: 10.5507/bp.2006.002. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2006. PMID: 16936898 Review.

8

Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine.

Stiborová M, Poljaková J, Ryslavá H, Dracínský M, Eckschlager T, Frei E. Stiborová M, et al. Int J Cancer. 2007 Jan 15;120(2):243-51. doi: 10.1002/ijc.22247. Int J Cancer. 2007. PMID: 17066455

9

Cytochromes P450 reconstituted with NADPH: P450 reductase mimic the activating and detoxicating metabolism of the anticancer drug ellipticine in microsomes.

Kotrbová V, Aimová D, Brezinová A, Janouchová K, Poljaková J, Frei E, Stiborová M. Kotrbová V, et al. Among authors: stiborova m. Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:18-22. Neuro Endocrinol Lett. 2006. PMID: 17159771

10

DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells.

Poljaková J, Frei E, Gomez JE, Aimová D, Eckschlager T, Hrabeta J, Stiborová M. Poljaková J, et al. Among authors: stiborova m. Cancer Lett. 2007 Jul 18;252(2):270-9. doi: 10.1016/j.canlet.2006.12.037. Epub 2007 Feb 16. Cancer Lett. 2007. PMID: 17306925

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