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Page 1
Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.
Mancuso DJ, Han X, Jenkins CM, Lehman JJ, Sambandam N, Sims HF, Yang J, Yan W, Yang K, Green K, Abendschein DR, Saffitz JE, Gross RW. Mancuso DJ, et al. Among authors: sambandam n. J Biol Chem. 2007 Mar 23;282(12):9216-27. doi: 10.1074/jbc.M607307200. Epub 2007 Jan 9. J Biol Chem. 2007. PMID: 17213206 Free article.
The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis.
Lehman JJ, Boudina S, Banke NH, Sambandam N, Han X, Young DM, Leone TC, Gross RW, Lewandowski ED, Abel ED, Kelly DP. Lehman JJ, et al. Among authors: sambandam n. Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H185-96. doi: 10.1152/ajpheart.00081.2008. Epub 2008 May 16. Am J Physiol Heart Circ Physiol. 2008. PMID: 18487436 Free PMC article.
CD36 deficiency rescues lipotoxic cardiomyopathy.
Yang J, Sambandam N, Han X, Gross RW, Courtois M, Kovacs A, Febbraio M, Finck BN, Kelly DP. Yang J, et al. Among authors: sambandam n. Circ Res. 2007 Apr 27;100(8):1208-17. doi: 10.1161/01.RES.0000264104.25265.b6. Epub 2007 Mar 15. Circ Res. 2007. PMID: 17363697
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.
Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED, Semenkovich CF, Kelly DP. Leone TC, et al. Among authors: sambandam n. PLoS Biol. 2005 Apr;3(4):e101. doi: 10.1371/journal.pbio.0030101. Epub 2005 Mar 15. PLoS Biol. 2005. PMID: 15760270 Free PMC article.
Akt2 regulates cardiac metabolism and cardiomyocyte survival.
DeBosch B, Sambandam N, Weinheimer C, Courtois M, Muslin AJ. DeBosch B, et al. Among authors: sambandam n. J Biol Chem. 2006 Oct 27;281(43):32841-51. doi: 10.1074/jbc.M513087200. Epub 2006 Aug 31. J Biol Chem. 2006. PMID: 16950770 Free PMC article.
Regulation of the PDK4 isozyme by the Rb-E2F1 complex.
Hsieh MCF, Das D, Sambandam N, Zhang MQ, Nahlé Z. Hsieh MCF, et al. Among authors: sambandam n. J Biol Chem. 2008 Oct 10;283(41):27410-27417. doi: 10.1074/jbc.M802418200. Epub 2008 Jul 30. J Biol Chem. 2008. PMID: 18667418 Free article.
Adaptation of myocardial substrate metabolism to a ketogenic nutrient environment.
Wentz AE, d'Avignon DA, Weber ML, Cotter DG, Doherty JM, Kerns R, Nagarajan R, Reddy N, Sambandam N, Crawford PA. Wentz AE, et al. Among authors: sambandam n. J Biol Chem. 2010 Aug 6;285(32):24447-56. doi: 10.1074/jbc.M110.100651. Epub 2010 Jun 7. J Biol Chem. 2010. PMID: 20529848 Free PMC article.
28 results