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Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons.
Ekstrand MI, Terzioglu M, Galter D, Zhu S, Hofstetter C, Lindqvist E, Thams S, Bergstrand A, Hansson FS, Trifunovic A, Hoffer B, Cullheim S, Mohammed AH, Olson L, Larsson NG. Ekstrand MI, et al. Among authors: terzioglu m. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1325-30. doi: 10.1073/pnas.0605208103. Epub 2007 Jan 16. Proc Natl Acad Sci U S A. 2007. PMID: 17227870 Free PMC article.
High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio.
Ross JM, Öberg J, Brené S, Coppotelli G, Terzioglu M, Pernold K, Goiny M, Sitnikov R, Kehr J, Trifunovic A, Larsson NG, Hoffer BJ, Olson L. Ross JM, et al. Among authors: terzioglu m. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20087-92. doi: 10.1073/pnas.1008189107. Epub 2010 Nov 1. Proc Natl Acad Sci U S A. 2010. PMID: 21041631 Free PMC article.
Mitochondrial dysfunction in mammalian ageing.
Terzioglu M, Larsson NG. Terzioglu M, et al. Novartis Found Symp. 2007;287:197-208; discussion 208-13. doi: 10.1002/9780470725207.ch14. Novartis Found Symp. 2007. PMID: 18074640 Review.
Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in Polg mutator mice.
Ahlqvist KJ, Hämäläinen RH, Yatsuga S, Uutela M, Terzioglu M, Götz A, Forsström S, Salven P, Angers-Loustau A, Kopra OH, Tyynismaa H, Larsson NG, Wartiovaara K, Prolla T, Trifunovic A, Suomalainen A. Ahlqvist KJ, et al. Among authors: terzioglu m. Cell Metab. 2012 Jan 4;15(1):100-9. doi: 10.1016/j.cmet.2011.11.012. Cell Metab. 2012. PMID: 22225879 Free article.
Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy.
Ignatenko O, Chilov D, Paetau I, de Miguel E, Jackson CB, Capin G, Paetau A, Terzioglu M, Euro L, Suomalainen A. Ignatenko O, et al. Among authors: terzioglu m. Nat Commun. 2018 Jan 4;9(1):70. doi: 10.1038/s41467-017-01859-9. Nat Commun. 2018. PMID: 29302033 Free PMC article.
86 results